CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007363
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcriptional repressor XBP1 
Protein Synonyms/Alias
 XhoI site-binding protein 1 
Gene Name
 XBP1 
Gene Synonyms/Alias
 YIL101C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
131DKNILMGKIILPSRSacetylation[1]
Reference
 [1] Preparative peptide isoelectric focusing as a tool for improving the identification of lysine-acetylated peptides from complex mixtures.
 Xie H, Bandhakavi S, Roe MR, Griffin TJ.
 J Proteome Res. 2007 May;6(5):2019-26. [PMID: 17397211
Functional Description
 Transcriptional repressor which binds to the consensus sequence 5'-GCCTCGA[G/A]G[C/A]-3'. Represses CLN1 transcription. 
Sequence Annotation
 DOMAIN 282 395 HTH APSES-type.
 DNA_BIND 318 339 H-T-H motif (By similarity).  
Keyword
 Complete proteome; DNA-binding; Nucleus; Reference proteome; Repressor; Stress response; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 647 AA 
Protein Sequence
MKYPAFSINS DTVHLTDNPL DDYQRLYLVS VLDRDSPPAS FSAGLNIRKV NYKSSIAAQF 60
THPNFIISAR DAGNGEEAAA QNVLNCFEYQ FPNLQTIQSL VHEQTLLSQL ASSATPHSAL 120
HLHDKNILMG KIILPSRSNK TPVSASPTKQ EKKALSTASR ENATSSLTKN QQFKLTKMDH 180
NLINDKLINP NNCVIWSHDS GYVFMTGIWR LYQDVMKGLI NLPRGDSVST SQQQFFCKAE 240
FEKILSFCFY NHSSFTSEES SSVLLSSSTS SPPKRRTSTG STFLDANASS SSTSSTQANN 300
YIDFHWNNIK PELRDLICQS YKDFLINELG PDQIDLPNLN PANFTKRIRG GYIKIQGTWL 360
PMEISRLLCL RFCFPIRYFL VPIFGPDFPK DCESWYLAHQ NVTFASSTTG AGAATAATAA 420
ANTSTNFTST AVARPRQKPR PRPRQRSTSM SHSKAQKLVI EDALPSFDSF VENLGLSSND 480
KNFIKKNSKR QKSSTYTSQT SSPIGPRDPT VQILSNLASF YNTHGHRYSY PGNIYIPQQR 540
YSLPPPNQLS SPQRQLNYTY DHIHPVPSQY QSPRHYNVPS SPIAPAPPTF PQPYGDDHYH 600
FLKYASEVYK QQNQRPAHNT NTNMDTSFSP RANNSLNNFK FKTNSKQ 647 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0043565; F:sequence-specific DNA binding; IDA:SGD.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:SGD.
 GO:0006950; P:response to stress; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR003163; Tscrpt_reg_HTH_APSES-type. 
Pfam
  
SMART
  
PROSITE
 PS51299; HTH_APSES 
PRINTS