CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039001
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 ATP-binding cassette sub-family D member 3 
Protein Synonyms/Alias
  
Gene Name
 Abcd3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
27KERAVVDKVFLSRLSacetylation[1]
226KMTIMEQKYEGEYRFacetylation[1]
226KMTIMEQKYEGEYRFubiquitination[2]
365TELMQVLKDLNHGKYacetylation[1]
495QVIYPDGKEDQKKKGacetylation[1]
499PDGKEDQKKKGISDQacetylation[1]
509GISDQVLKGYLDNVQacetylation[1]
614GRGNYEFKKITEDTVacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 625 AA 
Protein Sequence
LCSKKSGKPP LQNNEKEGKK ERAVVDKVFL SRLSQILKIM VPRTFCKETG YLILIAVMLV 60
SRTYCDVWMI QNGTLIESGI IGRSSKDFKR YLFNFIAAMP LISLVNNFLK YGLNELKLCF 120
RVRLTRYLYE EYLQAFTYYK MGNLDNRIAN PDQLLTQDVE KFCNSVVDLY SNLSKPFLDI 180
VLYIFKLTSA IGAQGPASMM AYLLVSGLFL TRLRRPIGKM TIMEQKYEGE YRFVNSRLIT 240
NSEEIAFYNG NKREKQTIHS VFRKLVEHLH NFIFFRFSMG FIDSIIAKYI ATVVGYLVVS 300
RPFLDLAHPR HLHSTHSELL EDYYQSGRML LRMSQALGRI VLAGREMTRL AGFTARITEL 360
MQVLKDLNHG KYERTMVSQQ DKGIEGAQAS PLIPGAGEII NADNIIKFDH VPLATPNGDI 420
LIQDLSFEVR SGANVLICGP NGCGKSSLFR VLGELWPLFG GHLTKPERGK LFYVPQRPYM 480
TLGTLRDQVI YPDGKEDQKK KGISDQVLKG YLDNVQLGHI LEREGGWDSV QDWMDVLSGG 540
EKQRMAMARL FYHKPQFAIL DECTSAVSVD VEDYIYSHCR KVGITLFTVS HRKSLWKHHE 600
YYLHMDGRGN YEFKKITEDT VEFGS 625 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR010509; ABC_Ald_N.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR017940; ABC_transporter_type1.
 IPR011527; ABC_transptrTM_dom_typ1.
 IPR005283; FA_transporter.
 IPR027417; P-loop_NTPase. 
Pfam
 PF06472; ABC_membrane_2
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS50929; ABC_TM1F
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS