CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039000
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Supt6h 
Protein Synonyms/Alias
  
Gene Name
 Supt6h 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1676HAAIDWGKMAEQWLQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1726 AA 
Protein Sequence
MSDFVESEAE ESEEEYNHEG EVVPRVTKKF VEEEDDGEEE EEENLDDQDE RGNLKDFIND 60
DDDEEEGEED EGSDSGDSED DVGHKKRKRT SFDDRLEDDD FDLIEENLGV KVKRGQKYRR 120
VKKMSDDDED DEEEYGKEEH EKEAIAGEIF QDEEGEEGQE AVEAPMAPPD EEEEDDEESD 180
IDDFIVDDDG QPLKKPKWRK KLPGYTDAAL QEAQEIFGVD FDYDEFEKYN EYDEELEEDY 240
EYEDDEAEGE IRVRPKKTTK KRVSRRSIFE MYEPSELESS HLTDQDNEIR ATDLPERFQL 300
RSIPVKAAED DELEEEADWI YRNAFATPTI SLQDSCDYLD RGQPTSSFSR KGPSTVQKIK 360
EALGFMRNQH FEVPFIAFYR KEYVEPELHI NDLWRVWQWD EKWTQLRIRK ENLTRLFEKM 420
QAYQYEQISA DPDKPLADGI RALDTTDMER LKDVQSMDEL KDVYNHFLLY YGRDIPKMQN 480
AAKASRKKLK RIKEDGDEEG EGEEAEDEEQ RGPELKQASR RDMYTICQSA GLDGLAKKFG 540
LTPEQFGENL RDSYQRHETE QFPAEPLELA KDYVCSQFPT PEAVLEGARY MVALQIAREP 600
LVRQVLRQTF QERAKLNITP TKKGRKDVDE AHYAYSFKYL KNKPVKELRD DQFLKIGLAE 660
DEGLLTIDIS IDMKGVEGYG NDQTYFEEIK QFYYRDEFSH QVQEWNRQRT MAIERALQQF 720
LYVQMAKELK NKLLAEARES VVKACSRKLY NWLRVAPYRP DQQVEEDDDF MDENQGKGIR 780
VLGIAFSSAR DHPVFCALVN GEGEVTDFLR LPHFTKRRTA WREEEREKKA QDIETLKKFL 840
VNKKPHVVTV AGENRDAQML IEDVKRIVHE LDQGQQLSSI GVELVDNELA ILYMNSKKSE 900
AEFRDYPPVL RQAVSLARRI QDPLIEFAQV CSSDEDILCL KFHPLQEHVV KEELLNALYC 960
EFINRVNEVG VDVNRAIAHP YSQALIQYVC GLGPRKGTHL LKILKQNNTR LESRTQLVTM 1020
CHMGPKVFMN CAGFLKIDTA SLGDSTDSYI EVLDGSRVHP ETYEWARKMA VDALEYDESA 1080
EDANPAGALE EILENPERLK DLDLDAFAEE LERQGYGDKH ITLYDIRAEL SCRYKDLRTA 1140
YRSPNTEEIF NMLTKETPET FYIGKLIICN VTGIAHRRPQ GESYDQAIRN DETGLWQCPF 1200
CQQDNFPELS EVWNHFDSGS CPGQAIGVKT RLDNGVTGFI PTKFLSDKVV KRPEERVKVG 1260
MTVHCRIMKI DIEKFSADLT CRTSDLMDRN NEWKLPKDTY YDFDAEAADH KQEEDMKRKQ 1320
QRTTYIKRVI AHPSFHNINF KQAEKMMETM DQGDVIIRPS SKGENHLTVT WKVSDGIYQH 1380
VDVREEGKEN AFSLGATLWI NSEEFEDLDE IVARYVQPMA SFARDLLNHK YYQDCSGGDR 1440
KKLEELLIKT KKEKPTFIPY FICACKELPG KFLLGYQPRG KPRIEYVTVT PEGFRYRGQI 1500
FPTVNGLFRW FKDHYQDPVP GITPSSSSRT RTPASINATP ANINLADLTR AVNALPQNMT 1560
SQMFSAIAAV TGQGQNPNAT PAQWASSQYG YGGSGGGSSA YHVFPTPAQQ PVATPLMTPS 1620
YSYTTPSQPI TTPQYHQLQA STTPQSTQAQ PQPSSSSRQR QQQPKSNSHA AIDWGKMAEQ 1680
WLQEKEAERR KQKQRLTPRP SPSPMIESTP MSIAGDATPL LDEMDR 1726 
Gene Ontology
 GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:InterPro.
 GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
 GO:0032784; P:regulation of DNA-dependent transcription, elongation; IEA:InterPro.
 GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IEA:InterPro. 
Interpro
 IPR012340; NA-bd_OB-fold.
 IPR003029; Rbsml_prot_S1_RNA-bd_dom.
 IPR022967; RNA-binding_domain_S1.
 IPR000980; SH2.
 IPR023323; Tex-like_dom.
 IPR023097; Tex_RuvX-like_dom.
 IPR017072; TF_Spt6.
 IPR006641; YqgF/RNaseH-like_dom. 
Pfam
 PF00575; S1
 PF00017; SH2 
SMART
 SM00316; S1
 SM00252; SH2
 SM00732; YqgFc 
PROSITE
 PS50126; S1
 PS50001; SH2 
PRINTS