UniProt Accession

 MYL3_RAT; P16409 

Genbank Protein ID

 X14812; X16325; X16326; X16327; X16329; X16330; BC081832 

Genbank Nucleotide ID

 CAA32917.1; CAA34388.1; CAA34388.1; CAA34388.1; CAA34388.1; CAA34388.1; AAH81832.1 

Protein Name

 Myosin light chain 3 

Protein Synonyms/Alias

 Myosin light chain 1, slow-twitch muscle B/ventricular isoform; MLC1SB; Ventricular/slow twitch myosin alkali light chain 

Gene Name

 Myl3 

Gene Synonyms/Alias

 Mlc1v 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
46	EAEFDASKIKIEFTP	acetylation	[1]
48	EFDASKIKIEFTPEQ	acetylation	[1]
60	PEQIEEFKEAFQLFD	acetylation	[1]
71	QLFDRTPKGEMKITY	acetylation	[1]
103	EVLRVLGKPKQEELN	acetylation	[1]
105	LRVLGKPKQEELNSK	acetylation	[1]
112	KQEELNSKMMDFETF	acetylation	[1]
130	LQHISKNKDTGTYED	acetylation	[1]
176	LTEDEVEKLMAGQED	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Regulatory light chain of myosin. Does not bind calcium. 

Sequence Annotation

 DOMAIN 54 91 EF-hand 1.
 DOMAIN 133 168 EF-hand 2.
 DOMAIN 168 200 EF-hand 3.
 MOD_RES 2 2 N,N,N-trimethylalanine (By similarity).  

Keyword

 Complete proteome; Methylation; Motor protein; Muscle protein; Myosin; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 200 AA 

Protein Sequence

Gene Ontology

 GO:0031672; C:A band; IEA:Compara.
 GO:0031674; C:I band; IEA:Compara.
 GO:0016459; C:myosin complex; IDA:RGD.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0003774; F:motor activity; IDA:RGD.
 GO:0060048; P:cardiac muscle contraction; IDA:RGD.
 GO:0006942; P:regulation of striated muscle contraction; IEA:Compara.
 GO:0002026; P:regulation of the force of heart contraction; IEA:Compara.
 GO:0007519; P:skeletal muscle tissue development; IEP:RGD.
 GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Compara. 

Interpro

 IPR011992; EF-hand-like_dom.
 IPR002048; EF_hand_dom. 

Pfam

 PF13405; EF_hand_4 

SMART

 SM00054; EFh 

PROSITE

 PS50222; EF_HAND_2 

PRINTS