CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005539
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L16-B 
Protein Synonyms/Alias
 L21; RP23; YL15 
Gene Name
 RPL16B 
Gene Synonyms/Alias
 RP23; RPL21B; YNL069C; N2377 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
11PVVVIDAKDHLLGRLacetylation[1]
24RLASTIAKQVLNGQKubiquitination[2]
31KQVLNGQKIVVVRAEubiquitination[2]
81APSRILYKAIRGMVSacetylation[1]
154KYEDVVAKLEDKRKVacetylation[1]
154KYEDVVAKLEDKRKVubiquitination[2]
176KKRAFTKKVSSASAAubiquitination[2, 3]
191ASESDVAKQLASFGYacetylation[1]
191ASESDVAKQLASFGYubiquitination[2]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [3] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047
Functional Description
  
Sequence Annotation
 MOD_RES 2 2 N-acetylserine; partial.
 MOD_RES 43 43 Phosphoserine.
 MOD_RES 181 181 Phosphoserine.
 MOD_RES 185 185 Phosphoserine.
 MOD_RES 187 187 Phosphoserine.  
Keyword
 Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 198 AA 
Protein Sequence
MSQPVVVIDA KDHLLGRLAS TIAKQVLNGQ KIVVVRAEAL NISGEFFRNK LKYHDFLRKA 60
TAFNKTRGPF HFRAPSRILY KAIRGMVSHK TARGKAALER LKIFEGIPPP YDKKKRVVVP 120
QALRVLRLKP GRKYTTLGKL STSVGWKYED VVAKLEDKRK VRSAEYYAKK RAFTKKVSSA 180
SAAASESDVA KQLASFGY 198 
Gene Ontology
 GO:0022625; C:cytosolic large ribosomal subunit; TAS:SGD.
 GO:0003723; F:RNA binding; IDA:SGD.
 GO:0003735; F:structural constituent of ribosome; TAS:SGD.
 GO:0002181; P:cytoplasmic translation; TAS:SGD. 
Interpro
 IPR005822; Ribosomal_L13.
 IPR023563; Ribosomal_L13_CS.
 IPR023564; Ribosomal_L13_dom.
 IPR005755; Ribosomal_L13_euk/arc. 
Pfam
 PF00572; Ribosomal_L13 
SMART
  
PROSITE
 PS00783; RIBOSOMAL_L13 
PRINTS