CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032066
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Src family associated phosphoprotein 2, isoform CRA_c 
Protein Synonyms/Alias
 Src kinase-associated phosphoprotein 2; cDNA FLJ50630, highly similar to Homo sapiens src family associated phosphoprotein 2 (SCAP2), mRNA 
Gene Name
 SCAP2 
Gene Synonyms/Alias
 SKAP2; hCG_38391 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
33QFTAASPKDAEEWVQubiquitination[1, 2]
103EEDSAPVKVEEQRKMubiquitination[2]
109VKVEEQRKMSQDSVHubiquitination[1]
157DVIYILSKEYNRYGWubiquitination[1, 2]
170GWWVGEMKGAIGLVPubiquitination[2]
178GAIGLVPKAYIMEMYubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 187 AA 
Protein Sequence
MNNTLRKDGK KDCCFEISAP DKRIYQFTAA SPKDAEEWVQ QLKFVLQDME SDIIPEDYDE 60
RGELYDDVDH PLPISNPLTS SQPIDDEIYE ELPEEEEDSA PVKVEEQRKM SQDSVHHTSG 120
DKSTDYANFY QGLWDCTGAF SDELSFKRGD VIYILSKEYN RYGWWVGEMK GAIGLVPKAY 180
IMEMYDI 187 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0008285; P:negative regulation of cell proliferation; IEA:Compara. 
Interpro
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology.
 IPR001452; SH3_domain. 
Pfam
 PF00018; SH3_1 
SMART
 SM00326; SH3 
PROSITE
 PS50003; PH_DOMAIN
 PS50002; SH3 
PRINTS
 PR00452; SH3DOMAIN.