CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015298
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 N-alpha-acetyltransferase 35, NatC auxiliary subunit 
Protein Synonyms/Alias
 Embryonic growth-associated protein; Protein MAK10 homolog 
Gene Name
 Naa35 
Gene Synonyms/Alias
 Egap; Mak10 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
82IGNQVNRKVLNFEQAubiquitination[1]
688SRILKVAKPNFVVMKubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Component of NAA50-NAA35 complex, which probably displays alpha (N-terminal) acetyltransferase activity. Regulates proliferation of smooth muscle cells. 
Sequence Annotation
  
Keyword
 Complete proteome; Cytoplasm; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 725 AA 
Protein Sequence
MVMKATVDDD ASGWELGVPE KMEKSSTSWV DITQDFEDAC RELKLGELLH DKLFGLFEAM 60
SAIEMMDPKM DAGMIGNQVN RKVLNFEQAI KDGTIKIKDL SLPELIGIMD TCFCCLITWL 120
EGHSLAQTVF TCLYIHNPDF IEDPAMKAFA LGILKICDIA REKVNKAAVF EEEDFQSMTY 180
GFKMANSVTD LRVTGMLKDV EDDLQRRVKS TRSRQGEERD PEVELEHQQC LAAFSRVKFT 240
RVLLTVLIAF TKKETSAVAE AQKLMVQAAD LLSAIHTSLH HGIQAQNGTT KGDHPIMMGF 300
EPLVNQRLLP PTFPRYAKII KREEMVNYFS RLIDRIKTVC EVVNLPNLHC ILDFFCEFSE 360
QSPCVLSRSL LQTTFLVDNK KVFGTHLMQD MVKDALRSFV SPPVLSPKCC LYNNHQAKDC 420
IDSFVTHCVR PFCSLVQIHG HNRARQRDKL GHILEEFATL QDEAEKVDAA LHTMLLKQEP 480
QRQHLACLGT WVLYHNLRIM IQYLLSGFEL ELYSMHEYYY IYWYLSEFLY AWLMSTLSRA 540
DGSQMAEERI MEEQQKGRSS KKTKKKKKVR PLSREITMSQ AYQNMCAGMF KTMVAFDMDG 600
KVRKPKFELD SEQVRYEHRF APFNSVMTPP PVHYLQFKEM SDLNKYSPPP QSPELYVAAS 660
KHFQQAKMIL ENIPNPDREV SRILKVAKPN FVVMKLLAGG HKKESKVPPE FDFSVHKYFP 720
VVKLV 725 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:UniProtKB.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0048659; P:smooth muscle cell proliferation; IMP:UniProtKB. 
Interpro
 IPR007244; NatC_AcTrfase_Mak10. 
Pfam
 PF04112; Mak10 
SMART
  
PROSITE
  
PRINTS