UniProt Accession

 EFP_THET8; Q76G20; Q5SJ89 

Genbank Protein ID

 AB103477; AP008226 

Genbank Nucleotide ID

 BAD14383.1; BAD70948.1 

Protein Name

 Elongation factor P 

Protein Synonyms/Alias

 EF-P 

Gene Name

 efp 

Gene Synonyms/Alias

 TTHA1125 

Created Date

 July 27, 2013 

Organism

 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) 

NCBI Taxa ID

 300852 

Lysine Modification

Position	Peptide	Type	References
29	CVEYQHQKLGRGGAK	acetylation	[1]

Reference

 [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus.
 Okanishi H, Kim K, Masui R, Kuramitsu S.
 J Proteome Res. 2013 Aug 1;. [PMID: 23901841] 

Functional Description

 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity). 

Sequence Annotation

  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Elongation factor; Protein biosynthesis; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 184 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003746; F:translation elongation factor activity; IEA:HAMAP.
 GO:0043043; P:peptide biosynthetic process; IEA:InterPro. 

Interpro

 IPR015365; Elong-fact-P_C.
 IPR012340; NA-bd_OB-fold.
 IPR014722; Rib_L2_dom2.
 IPR020599; Transl_elong_fac_P/YeiP.
 IPR013185; Transl_elong_KOW-like.
 IPR001059; Transl_elong_P/YeiP_cen.
 IPR013852; Transl_elong_P/YeiP_CS.
 IPR011768; Transl_elongation_fac_P.
 IPR008991; Translation_prot_SH3-like. 

Pfam

 PF01132; EFP
 PF08207; EFP_N
 PF09285; Elong-fact-P_C 

SMART

 SM00841; Elong-fact-P_C 

PROSITE

 PS01275; EFP 

PRINTS