CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013134
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transcription factor CP2-like protein 1 
Protein Synonyms/Alias
 CP2-related transcriptional repressor 1; CRTR-1 
Gene Name
 Tfcp2l1 
Gene Synonyms/Alias
 Crtr1; Tcfcp2l1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
84IRLLENRKLGDFQDLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Transcriptional suppressor. May suppress UBP1-mediated transcriptional activation. Required for normal duct development in the salivary gland and kidney. 
Sequence Annotation
 REGION 1 52 Mediate transcriptional repression.  
Keyword
 Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 479 AA 
Protein Sequence
MLFWHTQPEH YNQHNSGSYL RDVLALPIFK QEEPQLSPEN GARLPPLQYV LCAATSPAVK 60
LHEETLTYLN QGQSYEIRLL ENRKLGDFQD LNTKYVKSII RVVFHDRRLQ YTEYQQLEGW 120
RWSRPGDRIL DIDIPLSVGI LDPRASPTQL NAVEFLWDPS KRASAFIQVH CISTEFTPRK 180
HGGEKGVPFR VQIDTFKQNE SGDYSEHLHS ASCQIKVFKP KGADRKQKTD REKMEKRTAQ 240
EKEKYQPSYE TTILTECSPW PDVPYQANNT PSPSYNGSPN SFGLREGNSS PNHPVEPLPL 300
GSDHLLPSAS IQDAQQWLHR NRFSQFCWLF ASFSGADLLK MSRDDLVQVC GPADGIRLFN 360
AIKGRNVRPK MTIYVCQELE QNQLPLPQKQ DDSGDNSLCV YHAIFLEELT TLELTEKIAS 420
LYSIPPQHIH RVYRQGPAGI HVVVSNEMVQ NFQDESCFIL STLKAESNDG YHIILKCGL 479 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0016020; C:membrane; IDA:MGI.
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0005667; C:transcription factor complex; ISA:MGI.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0000902; P:cell morphogenesis; IMP:MGI.
 GO:0007028; P:cytoplasm organization; IMP:MGI.
 GO:0008340; P:determination of adult lifespan; IMP:MGI.
 GO:0002070; P:epithelial cell maturation; IMP:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
 GO:0045927; P:positive regulation of growth; IMP:MGI.
 GO:0007431; P:salivary gland development; IMP:MGI.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR007604; CP2.
 IPR013761; SAM/pointed. 
Pfam
 PF04516; CP2 
SMART
  
PROSITE
  
PRINTS