UniProt Accession

 RBL_ARATH; O03042 

Genbank Protein ID

 U91966; AP000423; AB003522; D88901 

Genbank Nucleotide ID

 AAB68400.1; BAA84393.1; BAA20946.1; BAA19595.1 

Protein Name

 Ribulose bisphosphate carboxylase large chain 

Protein Synonyms/Alias

 RuBisCO large subunit 

Gene Name

 rbcL 

Gene Synonyms/Alias

 AtCg00490 

Created Date

 July 27, 2013 

Organism

 Arabidopsis thaliana (Mouse-ear cress) 

NCBI Taxa ID

 3702 

Lysine Modification

Position	Peptide	Type	References
14	TKASVGFKAGVKEYK	acetylation	[1]
18	VGFKAGVKEYKLTYY	acetylation	[1]
21	KAGVKEYKLTYYTPE	acetylation	[1]
146	RIPPAYTKTFQGPPH	acetylation	[1]
175	PLLGCTIKPKLGLSA	acetylation	[1]
252	GTCEEMIKRAVFARE	acetylation	[2]
316	MHFRVLAKALRLSGG	acetylation	[1]
356	LRDDYVEKDRSRGIF	acetylation	[1]
463	AAACEVWKEITFNFP	acetylation	[1]

Reference

 [1] Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis.
 Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ.
 Plant Physiol. 2011 Apr;155(4):1779-90. [PMID: 21311031]
 [2] Lysine acetylation is a widespread protein modification for diverse proteins in Arabidopsis.
 Wu X, Oh MH, Schwarz EM, Larue CT, Sivaguru M, Imai BS, Yau PM, Ort DR, Huber SC.
 Plant Physiol. 2011 Apr;155(4):1769-78. [PMID: 21311030] 

Functional Description

 RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site (By similarity). 

Sequence Annotation

 ACT_SITE 175 175 Proton acceptor (By similarity).
 ACT_SITE 294 294 Proton acceptor (By similarity).
 METAL 201 201 Magnesium; via carbamate group (By
 METAL 203 203 Magnesium (By similarity).
 METAL 204 204 Magnesium (By similarity).
 BINDING 123 123 Substrate; in homodimeric partner (By
 BINDING 173 173 Substrate (By similarity).
 BINDING 177 177 Substrate (By similarity).
 BINDING 295 295 Substrate (By similarity).
 BINDING 327 327 Substrate (By similarity).
 BINDING 379 379 Substrate (By similarity).
 MOD_RES 3 3 N-acetylproline (By similarity).
 MOD_RES 14 14 N6,N6,N6-trimethyllysine (By similarity).
 MOD_RES 147 147 Phosphothreonine.
 MOD_RES 201 201 N6-carboxylysine (By similarity).
 MOD_RES 330 330 Phosphothreonine.
 DISULFID 247 247 Interchain; in linked form (By  

Keyword

 Acetylation; Calvin cycle; Carbon dioxide fixation; Chloroplast; Complete proteome; Disulfide bond; Lyase; Magnesium; Metal-binding; Methylation; Monooxygenase; Oxidoreductase; Phosphoprotein; Photorespiration; Photosynthesis; Plastid; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 479 AA 

Protein Sequence

Gene Ontology

 GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
 GO:0000287; F:magnesium ion binding; IEA:HAMAP.
 GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
 GO:0016984; F:ribulose-bisphosphate carboxylase activity; IEA:HAMAP.
 GO:0009853; P:photorespiration; IEA:UniProtKB-KW.
 GO:0019253; P:reductive pentose-phosphate cycle; IEA:UniProtKB-KW. 

Interpro

 IPR020878; RuBisCo_large_chain_AS.
 IPR020888; RuBisCO_lsu.
 IPR000685; RuBisCO_lsu_C.
 IPR017443; RuBisCO_lsu_fd_N.
 IPR017444; RuBisCO_lsu_N. 

Pfam

 PF00016; RuBisCO_large
 PF02788; RuBisCO_large_N 

SMART

  

PROSITE

 PS00157; RUBISCO_LARGE 

PRINTS