CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026327
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 WD repeat domain 3, isoform CRA_b 
Protein Synonyms/Alias
 cDNA FLJ77605, highly similar to Homo sapiens WD repeat domain 3 (WDR3), mRNA 
Gene Name
 WDR3 
Gene Synonyms/Alias
 hCG_37073 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
57WDLRKGEKILILQGLubiquitination[1]
521GGADKSVKFWDFELVubiquitination[1]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
 Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 943 AA 
Protein Sequence
MGLTKQYLRY VASAVFGVIG SQKGNIVFVT LRGEKGRYVA VPACEHVFIW DLRKGEKILI 60
LQGLKQEVTC LCPSPDGLHL AVGYEDGSIR IFSLLSGEGN VTFNGHKAAI TTLKYDQLGG 120
RLASGSKDTD IIVWDVINES GLYRLKGHKD AITQALFLRE KNLLVTSGKD TMVKWWDLDT 180
QHCFKTMVGH RTEVWGLVLL SEEKRLITGA SDSELRVWDI AYLQEIEDPE EPDPKKIKGS 240
SPGIQDTLEA EDGAFETDEA PEDRILSCRK AGSIMREGRD RVVNLAVDKT GRILACHGTD 300
SVLELFCILS KKEIQKKMDK KMKKARKKAK LHSSKGEEED PEVNVEMSLQ DEIQRVTNIK 360
TSAKIKSFDL IHSPHGELKA VFLLQNNLVE LYSLNPSLPT PQPVRTSRIT IGGHRSDVRT 420
LSFSSDNIAV LSAAADSIKI WNRSTLQCIR TMTCEYALCS FFVPGDRQVV IGTKTGKLQL 480
YDLASGNLLE TIDAHDGALW SMSLSPDQRG FVTGGADKSV KFWDFELVKD ENSTQKRLSV 540
KQTRTLQLDE DVLCVSYSPN QKLLAVSLLD CTVKIFYVDT LKFFLSLYGH KLPVICMDIS 600
HDGALIATGS ADRNVKIWGL DFGDCHKSLF AHDDSVMYLQ FVPKSHLFFT AGKDHKIKQW 660
DADKFEHIQT LEGHHQEIWC LAVSPSGDYV VSSSHDKSLR LWERTREPLI LEEEREMERE 720
AEYEESVAKE DQPAVPGETQ GDSYFTGKKT IETVKAAERI MEAIELYREE TAKMKEHKAI 780
CKAAGKEVPL PSNPILMAYG SISPSAYVLE IFKGIKSSEL EESLLVLPFS YVPDILKLFN 840
EFIQLGSDVE LICRCLFFLL RIHFGQITSN QMLVPVIEKL RETTISKVSQ VRDVIGFNMA 900
GLDYLKRECE AKSEVMFFAD ATSHLEEKKR KRKKREKLIL TLT 943 
Gene Ontology
 GO:0031965; C:nuclear membrane; IDA:HPA.
 GO:0005730; C:nucleolus; IDA:HPA. 
Interpro
 IPR020472; G-protein_beta_WD-40_rep.
 IPR007148; SSU_processome_Utp12.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF04003; Utp12
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00320; GPROTEINBRPT.