UniProt Accession

 UFC1_MOUSE; Q9CR09 

Genbank Protein ID

 AK003070; AK003897; BC021936 

Genbank Nucleotide ID

 BAB22546.1; BAB23063.1; AAH21936.1 

Protein Name

 Ubiquitin-fold modifier-conjugating enzyme 1 

Protein Synonyms/Alias

 Ufm1-conjugating enzyme 1 

Gene Name

 Ufc1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
33	ELWVQRLKEEYQSLI	ubiquitination	[1]
122	ICLTDHFKPLWARNV	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

 E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage (By similarity). 

Sequence Annotation

 ACT_SITE 116 116 Glycyl thioester intermediate (By  

Keyword

 Complete proteome; Reference proteome; Ubl conjugation pathway. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 167 AA 

Protein Sequence

Gene Ontology

 GO:0071568; F:UFM1 conjugating enzyme activity; ISS:UniProtKB.
 GO:0071569; P:protein ufmylation; ISS:UniProtKB. 

Interpro

 IPR016135; UBQ-conjugating_enzyme/RWD.
 IPR014806; Ufc1. 

Pfam

 PF08694; UFC1 

SMART

  

PROSITE

  

PRINTS