UniProt Accession

 PTCD2_MOUSE; Q8R3K3; Q91VG3; Q9D0S7 

Genbank Protein ID

 AK004502; BC016563; BC025110 

Genbank Nucleotide ID

 BAB23336.1; AAH16563.1; AAH25110.1 

Protein Name

 Pentatricopeptide repeat-containing protein 2, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 Ptcd2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
49	TDNIVKLKEFQHKKI	acetylation	[1]
54	KLKEFQHKKIAIAYN	acetylation	[2]

Reference

 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function. 

Sequence Annotation

 REPEAT 159 193 PPR.  

Keyword

 Complete proteome; Mitochondrion; mRNA processing; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 381 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0001822; P:kidney development; IMP:MGI.
 GO:0001889; P:liver development; IMP:MGI.
 GO:0007005; P:mitochondrion organization; IMP:MGI.
 GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
 GO:0048747; P:muscle fiber development; IMP:MGI.
 GO:0050684; P:regulation of mRNA processing; IMP:MGI.
 GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IMP:MGI. 

Interpro

 IPR002885; Pentatricopeptide_repeat.
 IPR019266; Ribosomal_S27_mit. 

Pfam

 PF10037; MRP-S27 

SMART

  

PROSITE

 PS51375; PPR 

PRINTS