Tag | Content |
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CPLM ID | CPLM-013476 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial |
Protein Synonyms/Alias | Complex I-42kD; CI-42kD; NADH-ubiquinone oxidoreductase 42 kDa subunit |
Gene Name | Ndufa10 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
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191 | VDHYNEIKRLTLPEY | acetylation | [1] | 228 | KGDPHEMKVTSAYLQ | acetylation | [1] | 242 | QDIEDAYKKTFLPKM | acetylation | [1] | 280 | IEYLNYNKGPWLKQD | acetylation | [1] | 285 | YNKGPWLKQDDRTFH | acetylation | [1] | 301 | LRMLVQDKREVLNYT | acetylation | [1] | 350 | YNADVGDKWIWLK** | acetylation | [1] |
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Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). |
Sequence Annotation | MOD_RES 122 122 N6-acetyllysine (By similarity). MOD_RES 181 181 N6-acetyllysine (By similarity). MOD_RES 242 242 N6-acetyllysine (By similarity). MOD_RES 350 350 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Complete proteome; Direct protein sequencing; Electron transport; FAD; Flavoprotein; Mitochondrion; Reference proteome; Respiratory chain; Transit peptide; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 355 AA |
Protein Sequence | MALRLLRLVP ASASARGLAA GAQRVGRIHT SVHCKLRYGL LASILGDKTT KKLHEYSRVI 60 TVDGNICSGK NKLARDIAEQ LGMKHYPEAG IQYSSSTTGD GRPLDIEFSG SCSLEKFYDN 120 PKSNDGNSYR LQSWLYASRL LQYSDALEHL LSTGQGVVLE RSIYSDFVFL EAMYNQGFIR 180 KQCVDHYNEI KRLTLPEYLP PHAVIYIDVP VSEIQSRIQK KGDPHEMKVT SAYLQDIEDA 240 YKKTFLPKMS EICEVLVYSS WEAEDSTKVV EDIEYLNYNK GPWLKQDDRT FHNLRMLVQD 300 KREVLNYTTV PVYLPEITIG AHQGSRIYDS FRELPGRKYA PGYNADVGDK WIWLK 355 |
Gene Ontology | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. GO:0005747; C:mitochondrial respiratory chain complex I; IEA:Compara. GO:0005524; F:ATP binding; IEA:InterPro. GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. GO:0022900; P:electron transport chain; IEA:UniProtKB-KW. GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro. GO:0042493; P:response to drug; IEP:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |