CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041024
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 ATP-binding cassette sub-family A member 8-A 
Protein Synonyms/Alias
  
Gene Name
 Abca8a 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
583LRLFAKIKGIQAHEVubiquitination[1]
619QNLSGGQKRKLTFGIubiquitination[1]
657HRVWNFLKERRADRVubiquitination[1]
691FISKGKLKCAGSSLFubiquitination[1]
734KQHIPDSKLSAESEGubiquitination[1]
742LSAESEGKLSYILPLubiquitination[1]
754LPLERTNKFPDLYRDubiquitination[1]
790VFLKLEGKSSIDQSDubiquitination[1]
1327LGHNGAGKSTSIKMIubiquitination[1]
1339KMITGETKPSAGQVLubiquitination[1]
1404ERLADALKLQDQLKSubiquitination[1]
1414DQLKSPVKTLSEGVKubiquitination[1]
1518YLLEMKVKTPSQVEPubiquitination[1]
1565PLSQAFFKLETVKQSubiquitination[1]
1610EELDPSVKWKLLPQEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1619 AA 
Protein Sequence
MVKREINVCQ QTWALLCKNL LRKKRLKRDT FLEFLYTALI LLSLILFLQL HEVYDFSSLP 60
DVDLGRIDSF NDSTFMIVYT PITPTTQRIM DRVSLVSYMT GRKILASPNE ENMTELISMR 120
FSDVVGVIFT NAYSYNLKFI KGARIPTIKE HQDHTAHCHS YGEIIYCGLS EFWRDGFVAL 180
QAAINAAIIE VTTNHSVMEE MMSLTGKYIK IDSFVGQEGT TTDCFLFFCI IRFSPLTYYI 240
SAGVTRERKK MKGLMAVMGL RDSAFWLSWG LLYGVIVFVV TLLSTTIVKL VQFVFLTGFM 300
VIFSLFFFYG LSLISLSFLM SVLLKKSFLT DLVVFLLTVS CGSLGFTALY RYLPVSLEWL 360
LSLLSPFAFM LGMVQLLRLD YDVNSNADPM GNPNEVIGTI FMLFFDGVFY LLLTFYFEKV 420
LPSEYGRRHP PLFFLKSSFW SGQNPANRTA LDNETDYEFS DDSFEPVSME FHGKEAIRIR 480
NLTKDYIQKS KRTEALKDLT LDVYKGQITA ILGHSGAGKS TLLNVLSGLC VPTKGWVTIH 540
NNKLSEMTDL ENISKLTGVC PQCNVQFDFL TVRENLRLFA KIKGIQAHEV DNEVQRVLLE 600
LDMKNTQNIL VQNLSGGQKR KLTFGIAILG DPQIFLLDEP TAGLDPFSRH RVWNFLKERR 660
ADRVVLFSTQ FMDEADILAD RKVFISKGKL KCAGSSLFLK KKWGIGYHLS LQLSETCVHE 720
RITSLVKQHI PDSKLSAESE GKLSYILPLE RTNKFPDLYR DLERSPDLGI ENYGVSITTL 780
TEVFLKLEGK SSIDQSDIGM TEDVQAGGAR SPERFAEVEQ LVSLLNGRCK MKGGMALWWQ 840
QLCAVTRLRF LKLKHERKSI VILILVLGIG LLHILSANIY RMVRQSDYCW ELAPHMYFLT 900
PGQQPQPPLT NLLIVNKTGA KIDDFIHSLE QQNIALEVDA FGTRNGTEDS QYNGAIILSG 960
DEKNYNFTLA CNTKRLNCFP VLVDIVSNGL LGLFAPSAHI QTDRSTFPEE NDHRKFDYLA 1020
YFFLWVLLMA CVPPYISMTS IDDYKNRAQF QLWISGLSPS AYWFGQALFE VPVYCALILS 1080
IFIAFYASAP PESKFTVGDL FIQILYVGGY AMSVIFMTYV ISFIYRKGRK NSGLWSLCFY 1140
IVSFFSMCFM LIDYFRDISL FVLIALVPPA TLGGCTLLHF ENREFSEIIF EPEREYSYLF 1200
FLAPLLHFAI FVVILRCMER KFGMKTMRTD PVFRISPRSD RVFNNPEDPD GEDEDVSQER 1260
VWTANALTSA DFQEKPAIIA SCLRKEYKGK KKCFVLKSKK KIATRNISFC VRKGEVVGLL 1320
GHNGAGKSTS IKMITGETKP SAGQVLLKGS STGDTPGFLG YCPQENALWL NLTVREHLEI 1380
FAAIKGMRKS DANVAIERLA DALKLQDQLK SPVKTLSEGV KRKLCFVLSI LGNPSVVLLD 1440
EPSTGMDPEG QQQMWQAIQA TFSNTERGAL LTTHYMAEAE AVCDRVAIMV SGRLRCIGSI 1500
QHLKSKFGKE YLLEMKVKTP SQVEPLNTEI MRLFPQAARQ ERYSSLMVYK LPREDVQPLS 1560
QAFFKLETVK QSFDLEEYSL SQSTLEQVFL ELSKEQELDG FEEELDPSVK WKLLPQEEA 1619 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR026082; ABC_A.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS