CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028292
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Interferon-g induced GTPase 
Protein Synonyms/Alias
 Interferon-gamma-inducible GTPase Ifggd2 protein; Protein Irgm2 
Gene Name
 Irgm2 
Gene Synonyms/Alias
 AI481100; GTPI; Ifggd2; Iigp2 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
316VALEMKNKHFNTSMEubiquitination[1]
379ILDETAAKAKEVLLKubiquitination[1]
386KAKEVLLKILRLSIPubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 395 AA 
Protein Sequence
MEEAVESPEV KEFEYFSDAV FIPKDGNTLS VGVIKRIETA VKEGEVVKVV SIVKEIIQNV 60
SRNKIKIAVT GDSGNGMSSF INALRLIGHE EKDSAPTGVV RTTQKPTCYF SSHFPYVELW 120
DLPGLGATAQ SVESYLEEMQ ISIYDLIIIV ASEQFSLNHV KLAITMQRMR KRFYVVWTKL 180
DRDLSTSTFP EPQLLQSIQR NIRDSLQKEK VKEHPMFLVS VFKPESHDFP KLRETLQKDL 240
PVIKYHGLVE TLYQVCEKTV NERVESIKKS IDEDNLHTEF GISDPGNAIE IRKAFQKTFG 300
LDDISLHLVA LEMKNKHFNT SMESQETQRY QQDDWVLARL YRTGTRVGSI GFDYMKCCFT 360
SHHSRCKQQK DILDETAAKA KEVLLKILRL SIPHP 395 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IDA:UniProtKB.
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0020003; C:symbiont-containing vacuole; IDA:UniProtKB.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0003924; F:GTPase activity; ISS:MGI.
 GO:0042742; P:defense response to bacterium; IMP:UniProtKB.
 GO:0042832; P:defense response to protozoan; IDA:UniProtKB.
 GO:0034341; P:response to interferon-gamma; IDA:UniProtKB. 
Interpro
 IPR007743; Interferon-induced_GTPase.
 IPR027417; P-loop_NTPase. 
Pfam
 PF05049; IIGP 
SMART
  
PROSITE
  
PRINTS