CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010258
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable transcriptional regulatory protein YedW 
Protein Synonyms/Alias
  
Gene Name
 yedW 
Gene Synonyms/Alias
 b1969; JW5322 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
100GANDYLVKPFSFSELacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 Probable member of a two-component regulatory system YedW/YedV. 
Sequence Annotation
 DOMAIN 1 115 Response regulatory.
 MOD_RES 51 51 4-aspartylphosphate (By similarity).  
Keyword
 Complete proteome; Cytoplasm; DNA-binding; Phosphoprotein; Reference proteome; Transcription; Transcription regulation; Two-component regulatory system. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 223 AA 
Protein Sequence
MKILLIEDNQ RTQEWVTQGL SEAGYVIDAV SDGRDGLYLA LKDDYALIIL DIMLPGMDGW 60
QILQTLRTAK QTPVICLTAR DSVDDRVRGL DSGANDYLVK PFSFSELLAR VRAQLRQHHA 120
LNSTLEISGL RMDSVSHSVS RDNISITLTR KEFQLLWLLA SRAGEIIPRT VIASEIWGIN 180
FDSDTNTVDV AIRRLRAKVD DPFPEKLIAT IRGMGYSFVA VKK 223 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:GOC.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR011006; CheY-like_superfamily.
 IPR001867; Sig_transdc_resp-reg_C.
 IPR016032; Sig_transdc_resp-reg_C-effctor.
 IPR006291; Sig_transdc_resp-reg_metal.
 IPR001789; Sig_transdc_resp-reg_receiver.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00072; Response_reg
 PF00486; Trans_reg_C 
SMART
 SM00448; REC
 SM00862; Trans_reg_C 
PROSITE
 PS50110; RESPONSE_REGULATORY 
PRINTS