CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026360
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 FK506 binding protein 5 
Protein Synonyms/Alias
 Protein Fkbp5; RCG60597 
Gene Name
 Fkbp5 
Gene Synonyms/Alias
 rCG_60597 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
83PFVFSLGKGQVIKAWacetylation[1]
431EASKALSKKAVEGAAacetylation[1]
440AVEGAAGKKHESQTMacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 456 AA 
Protein Sequence
MTTDEGTSNN EENPAATVVE QGEDITTKKD RGVLKIVKRV GTSEETPMIG DKVYVHYKGK 60
LSNGKKFDSS RDRNEPFVFS LGKGQVIKAW DIGVSTMKKG EICHLLCKPE YAYGSAGSLP 120
KIPSNATLFF EIELLDFKGE DLFEDSGIIR RIKRKGEGYS NPNEGATVEV HLEGCCAGRV 180
FDCRDVVFVI GEGEDHDIPI GIDKALEKMQ REEQCILYLG PQYGFGEAGK PKFGIEPNAE 240
LMYEVTLKSF EKAKESWEMD TKEKLEQAAI VKEKGTVYFK GGKYMQAVIQ YGKIVSWLEM 300
EYGLSEKESK ASESFLLAAF LNLAMCYLKL REYTKAVECC DKALGLDSAN EKGLYRRGEA 360
QLLMNEFESA KGDFEKVLEV NPQNKAARLQ ISVCQRKAKE HNERDRRVYA NMFKKFAEQD 420
AKEEASKALS KKAVEGAAGK KHESQTMGEG KAEGHV 456 
Gene Ontology
 GO:0016020; C:membrane; IBA:RefGenome.
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005528; F:FK506 binding; IBA:RefGenome.
 GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IBA:RefGenome.
 GO:0061077; P:chaperone-mediated protein folding; IEA:Compara. 
Interpro
 IPR023114; Elongated_TPR_rpt_dom.
 IPR023566; PPIase_FKBP.
 IPR001179; PPIase_FKBP_dom.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 
Pfam
 PF00254; FKBP_C 
SMART
  
PROSITE
 PS50059; FKBP_PPIASE
 PS50005; TPR
 PS50293; TPR_REGION 
PRINTS