CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028530
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cyclin-dependent kinase 11B 
Protein Synonyms/Alias
  
Gene Name
 Cdk11b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
219GDNRKPVKEEKVEERacetylation[1]
519WILHRDLKTSNLLLSubiquitination[2]
596QKPLFPGKSDIDQINubiquitination[2]
604SDIDQINKIFKDLGTubiquitination[2]
615DLGTPSEKIWPGYNDubiquitination[2]
628NDLPAVKKMTFSEYPubiquitination[2]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 750 AA 
Protein Sequence
MSQSDDRDSK RDSLEEGELR DHRMEITIRN SPYRREDSME DRGEEDDSLA IKPPQQMSRK 60
EKAHHRKDEK RKEKRRHRSH SAEGGKHARV KEKEREHERR KRHREEQDKA RREWERQKRR 120
EMAREHSRRE RDRLEQLERK RERERKLREQ QKEQREQKER ERRAEERRKE REARREVSAH 180
HRTMREEYSD KGKVGHWSRS PLRPPRERFE MGDNRKPVKE EKVEERDLLS DLQDISDSER 240
KTSSAESSSA ESGSGSEEEE EEEEEEEEEE GSTSEESEEE EEEEEEEEEE ETGSNSEEAS 300
EQSAEEVSDE EMSEDEDREN ENHILVVPES RFDRDSGDSE EGEEEVGEGT PQSSAPTEGD 360
YVPDSPALSP IELKQELPKY LPALQGCRSV EEFQCLNRIE EGTYGVVYRA KDKKTDEIVA 420
LKRLKMEKEK EGFPITSLRE INTILKAQHP NIVTVREIVV GSNMDKIYIV MNYVEHDLKS 480
LMETMKQPFL PGEVKTLMIQ LLSGVKHLHD NWILHRDLKT SNLLLSHAGI LKVGDFGLAR 540
EYGSPLKAYT PVVVTLWYRA PELLLGAKEY STAVDMWSVG CIFGELLTQK PLFPGKSDID 600
QINKIFKDLG TPSEKIWPGY NDLPAVKKMT FSEYPYNNLR KRFGALLSDQ GFDLMNKFLT 660
YYPGRRINAE DGLKHEYFRE TPLPIDPSMF PTWPAKSEQQ RVKRGTSPRP PEGGLGYSQL 720
GDDDLKETGF HLTTTNQGAS AAGPGFSLKF 750 
Gene Ontology
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:InterPro.
 GO:0006915; P:apoptotic process; IMP:MGI.
 GO:0001824; P:blastocyst development; IMP:MGI.
 GO:0007088; P:regulation of mitosis; IMP:MGI. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00069; Pkinase 
SMART
 SM00220; S_TKc 
PROSITE
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS