| Tag | Content |
|---|
| CPLM ID | CPLM-018524 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Podocin |
Protein Synonyms/Alias | |
Gene Name | Nphs2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 301 | VIAAEGEKAASESLR | ubiquitination | [1] | | 370 | INYPSSSKPVEPLNP | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton (By similarity). |
Sequence Annotation | LIPID 103 103 S-palmitoyl cysteine (By similarity). |
Keyword | Complete proteome; Lipoprotein; Membrane; Palmitate; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 385 AA |
Protein Sequence | MDSRARSSSR EAHGRSSRSS SRDDKKAKAG RGSRGRARPD AGAERQSTGR TATRGEPRAP 60
AATATVVDVD EVRGPGEEGT EVVALLESER PEEGIKPSGL GACEWLLVLA SLIFIIMTFP 120
FSIWFCIKVV QEYERVIIFR LGHLLPGRAK GPGLFFFLPC LDTYHKVDLR LQTLEIPFHE 180
VVTKDMFIME IDAVCYYRME NASLLLSSLA HVSKAIQFLV QTTMKRLLAH RSLTEILLER 240
KSIAQDVKVA LDAVTCIWGI KVERTEIKDV RLPAGLQHSL AVEAEAQRQA KVRVIAAEGE 300
KAASESLRMA AEILSGTPAA VQLRYLHTLQ SLSTEKPATV VLPLPFDMLS LLSSPGNRAQ 360
GSINYPSSSK PVEPLNPKKK DSPML 385 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0031235; C:intrinsic to internal side of plasma membrane; IDA:UniProtKB. GO:0045121; C:membrane raft; IEA:Compara. GO:0043234; C:protein complex; IEA:Compara. GO:0036057; C:slit diaphragm; IEA:Compara. GO:0031532; P:actin cytoskeleton reorganization; IEA:Compara. GO:0072249; P:metanephric glomerular visceral epithelial cell development; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |