CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028867
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Disks large homolog 3 
Protein Synonyms/Alias
  
Gene Name
 Dlg3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
747DVSGNAIKRLQQAQLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 835 AA 
Protein Sequence
MHKHQHCCKC PECYEVTRLA ALRRLEPPGY GDWQVPDPYG PSGGNGASSG YGGYSSQTLP 60
SQAGATPTPR TKAKLIPTGR DVGPVPPKPV PGKSTPKLNG SGPGWWPECT CTNRDWYEQA 120
SPAPLLVNPE ALEPSLSVNG SDGMFKYEEI VLERGNSGLG FSIAGGIDNP HVPDDPGIFI 180
TKIIPGGAAA MDGRLGVNDC VLRVNEVDVS EVVHSRAVEA LKEAGPVVRL VVRRRQPPPE 240
TIMEVNLLKG PKGLGFSIAG GIGNQHIPGD NSIYITKIIE GGAAQKDGRL QIGDRLLAVN 300
NTNLQDVRHE EAVASLKNTS DMVYLKVAKP GSIHLNDMYA PPDYASTFTA LADNHISHNS 360
SLGYLGAVES KVTYPAPPQV PPTRYSPIPR HMLAEEDFTR EPRKIILHKG STGLGFNIVG 420
GEDGEGIFVS FILAGGPADL SGELRRGDRI LSVNGVNLRN ATHEQAAAAL KRAGQSVTIV 480
AQYRPEEYSR FESKIHDLRE QMMNSSMSSG SGSLRTSEKR SLYVRALFDY DRTRDSCLPS 540
QGLSFSYGDI LHVINASDDE WWQARLVTPH GESEQIGVIP SKKRVEKKER ARLKTVKFHA 600
RTGMIESNRD FPGLSDDYYG AKNLKGQEDA ILSYEPVTRQ EIHYARPVII LGPMKDRVND 660
DLISEFPHKF GSCVPHTTRP RRDNEVDGQD YHFVVSREQM EKDIQDNKFI EAGQFNDNLY 720
GTSIQSVRAV AERGKHCILD VSGNAIKRLQ QAQLYPIAIF IKPKSIEALM EMNRRQTYEQ 780
ANKIFDKAMK LEQEFGEYFT AIVQGDSLEE IYNKIKQIIE DQSGHYIWVP SPEKL 835 
Gene Ontology
 GO:0032281; C:alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex; IDA:MGI.
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005923; C:tight junction; IDA:MGI.
 GO:0001736; P:establishment of planar polarity; IMP:MGI.
 GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; IMP:MGI. 
Interpro
 IPR008144; Guanylate_kin.
 IPR008145; Guanylate_kin/L-typ_Ca_channel.
 IPR020590; Guanylate_kinase_CS.
 IPR016313; M-assoc_guanylate_kinase.
 IPR019590; MAGUK_PEST_N.
 IPR027417; P-loop_NTPase.
 IPR001478; PDZ.
 IPR019583; PDZ_assoc.
 IPR001452; SH3_domain. 
Pfam
 PF00625; Guanylate_kin
 PF10608; MAGUK_N_PEST
 PF00595; PDZ
 PF10600; PDZ_assoc
 PF00018; SH3_1 
SMART
 SM00072; GuKc
 SM00228; PDZ
 SM00326; SH3 
PROSITE
 PS00856; GUANYLATE_KINASE_1
 PS50052; GUANYLATE_KINASE_2
 PS50106; PDZ
 PS50002; SH3 
PRINTS