CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-010136
UniProt Accession
Genbank Protein ID
 U00089 
Genbank Nucleotide ID
Protein Name
 Ribonuclease Y 
Protein Synonyms/Alias
 RNase Y 
Gene Name
 rny 
Gene Synonyms/Alias
 MPN_269; A65_orf493; MP564 
Created Date
 July 27, 2013 
Organism
 Mycoplasma pneumoniae (strain ATCC 29342 / M129) 
NCBI Taxa ID
 272634 
Lysine Modification
Position
Peptide
Type
References
148FHKRLFNKFHFGVDKacetylation[1]
408SVLFSQLKQELKQIVacetylation[1]
Reference
 [1] Cross-talk between phosphorylation and lysine acetylation in a genome-reduced bacterium.
 van Noort V, Seebacher J, Bader S, Mohammed S, Vonkova I, Betts MJ, Kühner S, Kumar R, Maier T, O'Flaherty M, Rybin V, Schmeisky A, Yus E, Stülke J, Serrano L, Russell RB, Heck AJ, Bork P, Gavin AC.
 Mol Syst Biol. 2012 Feb 28;8:571. [PMID: 22373819] 
Functional Description
 Endoribonuclease that initiates mRNA decay (By similarity). 
Sequence Annotation
 DOMAIN 172 241 KH.
 DOMAIN 300 391 HD.  
Keyword
 Cell membrane; Complete proteome; Endonuclease; Hydrolase; Membrane; Nuclease; Reference proteome; RNA-binding; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 493 AA 
Protein Sequence
MSAKLTLESI AKTFAETSIF AILFLIIVIL NLGLLVFLAY QYRVYKKKQR ANLTKQTYNN 60
DYGQIVNLKQ QNGAKIKELA NLKDQLSELG QKFNTTLSEI INKPLVNVID EYLDEQFKQA 120
ANFREAELNA VLDSNDQKTV FHKRLFNKFH FGVDKLANIN VKNPLNLCWV DSASFTVIES 180
DFRKLNGVGG INKKLLIEKL RIEDIIFTNI DKKYYEVQIL SDSPVKVQKT VLTIRNILIN 240
DYVDNEKIES YAREANGYFN DHCKLIGKQV LERLNIFEIS PKLHKFFGLL AFRYSFGQNV 300
LSHCLETGFL TAYLALLVNF KPDVALKCGL YHDIGKADDE NGKKNHTVTG AKIGDEFYFE 360
NDVKYTIANH HNKNVDNVYC RLTQIGDKLS AGRLGARSDS SVLFSQLKQE LKQIVEETLA 420
QFKTTILLGQ SGRRLVIWLE TNQHNNIIDN QQLTDLATTI KSKIVQNNIT NRFPIKVVLR 480
YNFEHSFDTK DKN 493 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0004521; F:endoribonuclease activity; IEA:HAMAP.
 GO:0046872; F:metal ion binding; IEA:InterPro.
 GO:0008081; F:phosphoric diester hydrolase activity; IEA:InterPro.
 GO:0003723; F:RNA binding; IEA:HAMAP.
 GO:0006402; P:mRNA catabolic process; IEA:HAMAP. 
Interpro
 IPR003607; HD/PDEase_dom.
 IPR006674; HD_domain.
 IPR017705; Ribonuclease_Y.
 IPR006675; Uncharacterised_HDIG. 
Pfam
 PF01966; HD 
SMART
 SM00471; HDc 
PROSITE
 PS50084; KH_TYPE_1 
PRINTS