CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027299
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATPase and permease components of ABC-type multidrug transport system 
Protein Synonyms/Alias
  
Gene Name
 mdlB 
Gene Synonyms/Alias
 LA_3694 
Created Date
 July 27, 2013 
Organism
 Leptospira interrogans serogroup Icterohaemorrhagiae serovar La 
NCBI Taxa ID
 189518 
Lysine Modification
Position
Peptide
Type
References
44FEISLTKKDKILLQRmethylation[1]
Reference
 [1] High-coverage proteome analysis reveals the first insight of protein modification systems in the pathogenic spirochete Leptospira interrogans.
 Cao XJ, Dai J, Xu H, Nie S, Chang X, Hu BY, Sheng QH, Wang LS, Ning ZB, Li YX, Guo XK, Zhao GP, Zeng R.
 Cell Res. 2010 Feb;20(2):197-210. [PMID: 19918266] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 609 AA 
Protein Sequence
MTLGIVLSFL VSILNGASLT SLIPIFDSLG TGEKTNFEIS LTKKDKILLQ RLEEKESFTS 60
VESIELKLAQ WKIQLNSSLK KMSHDELVLL FCFIVFPVYL LKLIFLAAAV YCINSAGYLA 120
IRDLRSELYA KAQTLPINHF VQEKTGILMS RIINDVEVLG KLISSDLKDA ITDFFYIVTH 180
LLLLLYLSWK MFLAVFIVVP IVMGPVSAFA DKIRRATRNQ QERLSLLNGH LQEVISGIRV 240
IRAFSMEKTE AKRFWEFNQD LSDKTFKGHF YHQVGPSLTE LFSSIVAVIF LSFGAYLMED 300
GTFSRGMFMA FFLTLIFLMR PFKQMSMLSN SIQSAISAGD RVFELLDQET DIRNPANPKF 360
LKKMEKGLSF NNVTYMYPGA KNPAIQEINL EIAKGETIAL VGASGAGKST LVDLVPRLID 420
PQEGKVLIDG IDLRDLDLSN LRKRIGIVSQ QVFLFNGSIR ENICYGNQNV TEEQLRTACE 480
QAFAMEFILS FEEGLDTIVG ERGVMLSGGQ RQRIAIARAL LLNPEILILD EATSALDTES 540
ERLVQEALES LYKNRTVIII AHRLSTVQIA NRIFTMEDGK IVESGTHTEL LQLDGKYKKL 600
YDIQFSENV 609 
Gene Ontology
 GO:0016021; C:integral to membrane; IBA:RefGenome.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0034040; F:lipid-transporting ATPase activity; IBA:RefGenome. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR017940; ABC_transporter_type1.
 IPR001140; ABC_transptr_TM_dom.
 IPR011527; ABC_transptrTM_dom_typ1.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00664; ABC_membrane
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS50929; ABC_TM1F
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS