CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-022269
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 F-box only protein 34 
Protein Synonyms/Alias
  
Gene Name
 FBXO34 
Gene Synonyms/Alias
 FBX34 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
86VESSLNVKTKKNAPSubiquitination[1]
227ALLASCSKNCTNSPAubiquitination[1]
552LEASSWKKQVSHDFLubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity). 
Sequence Annotation
 DOMAIN 572 624 F-box.  
Keyword
 Complete proteome; Polymorphism; Reference proteome; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 711 AA 
Protein Sequence
MHLKPYWKLQ KKEHPPEVSR ETQRTPMNHQ KAVNDETCKA SHITSSVFPS ASLGKASSRK 60
PFGILSPNVL CSMSGKSPVE SSLNVKTKKN APSATIHQGE EEGPLDIWAV VKPGNTKEKI 120
AFFASHQCSN RIGSMKIKSS WDIDGRATKR RKKSGDLKKA KVQVERMREV NSRCYQPEPF 180
ACGIEHCSVH YVSDSGDGVY AGRPLSVIQM VAFLEQRASA LLASCSKNCT NSPAIVRFSG 240
QSRGVPAVSE SYSAPGACEE PTERGNLEVG EPQSEPVRVL DMVAKLESEC LKRQGQREPG 300
SLSRNNSFRR NVGRVLLANS TQADEGKTKK GVLEAPDTQV NPVGSVSVDC GPSRADRCSP 360
KEDQAWDGAS QDCPPLPAGV SFHIDSAELE PGSQTAVKNS NRYDVEMTDE LVGLPFSSHT 420
YSQASELPTD AVDCMSRELV SLTSRNPDQR KESLCISITV SKVDKDQPSI LNSCEDPVPG 480
MLFFLPPGQH LSDYSQLNES TTKESSEASQ LEDAAGGDSA SEEKSGSAEP FVLPASSVES 540
TLPVLEASSW KKQVSHDFLE TRFKIQQLLE PQQYMAFLPH HIMVKIFRLL PTKSLVALKC 600
TCCYFKFIIE YYNIRPADSR WVRDPRYRED PCKQCKKKYV KGDVSLCRWH PKPYCQALPY 660
GPGYWMCCHR SQKGFPGCKL GLHDNHWVPA CHSFNRAIHK KAKGTEAEEE Y 711 
Gene Ontology
  
Interpro
 IPR001810; F-box_dom_cyclin-like. 
Pfam
  
SMART
 SM00256; FBOX 
PROSITE
 PS50181; FBOX 
PRINTS