UniProt Accession

 E9Q3E3_MOUSE; E9Q3E3 

Genbank Protein ID

 AC121908 

Genbank Nucleotide ID

  

Protein Name

 Glycine receptor subunit beta 

Protein Synonyms/Alias

  

Gene Name

 Glrb 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
117	KWNDPRLKLPSDFRG	ubiquitination	[1]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Ion channel; Ion transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 307 AA 

Protein Sequence

Gene Ontology

 GO:0005783; C:endoplasmic reticulum; ISA:MGI.
 GO:0009897; C:external side of plasma membrane; ISA:MGI.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0045211; C:postsynaptic membrane; IEA:InterPro.
 GO:0016934; F:extracellular-glycine-gated chloride channel activity; IMP:MGI.
 GO:0016594; F:glycine binding; IMP:MGI.
 GO:0007340; P:acrosome reaction; IMP:MGI.
 GO:0007628; P:adult walking behavior; IMP:MGI.
 GO:0050905; P:neuromuscular process; IMP:MGI.
 GO:0042391; P:regulation of membrane potential; IMP:MGI.
 GO:0060013; P:righting reflex; IMP:MGI.
 GO:0060012; P:synaptic transmission, glycinergic; IMP:MGI.
 GO:0007601; P:visual perception; IMP:MGI. 

Interpro

 IPR008060; Glycine_rcpt_B.
 IPR006202; Neur_chan_lig-bd.
 IPR006201; Neur_channel.
 IPR006029; Neurotrans-gated_channel_TM.
 IPR018000; Neurotransmitter_ion_chnl_CS. 

Pfam

 PF02931; Neur_chan_LBD
 PF02932; Neur_chan_memb 

SMART

  

PROSITE

 PS00236; NEUROTR_ION_CHANNEL 

PRINTS

 PR01677; GLYRBETA.
 PR00252; NRIONCHANNEL.