CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034895
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Condensin complex subunit 1 
Protein Synonyms/Alias
  
Gene Name
 Ncapd2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
148IDLDIGGKGKKARAKacetylation[1]
150LDIGGKGKKARAKTAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
 Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity). 
Sequence Annotation
  
Keyword
 Cell cycle; Cell division; Complete proteome; DNA condensation; Mitosis; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1390 AA 
Protein Sequence
MSPHNFEFHL PLSPEELLKS RGVNQYVVQE VLPIKHLPTQ LRAFQSAFRA QGPLAILDHF 60
DTIYSIIHHF RSIEPGLKED TLEFLMKVVS CHSQELSSIL DDAALSGSDR SAHLNALKMN 120
CYALIRLLES FENMTSQTGL IDLDIGGKGK KARAKTALGF VWEEERQPVL ELLTQLLQLD 180
IRHLWSHSVI EEEFVSLVTG CCYRLLENPT ISHQKNRSTK EAIAHLLGVA LVRYNHMLSA 240
TVKIIQMLQH FEHLPSVLVA AVTLWATDYG MKSIVGEIVR EIGQKCPQEM SRDTAGAKGF 300
AAFLTELAER IPAALMSSMC MLLDHLDGEN YMMRNAVLAA MAEMILQVLN GDQLEESARE 360
TRDQFLDILQ AHGHDVNSFV RSRVLQLFTR IVQQKALPLT RFQAVVALAV GRLADKSVLV 420
CKNAIQLLAS FLANNPFSCK LSDTDLAGPL QKEIQKLQEM RAQRRTAAAS AALDSEEEWE 480
AMLPELKSTV QQLLKLPQEE AEQQIADGET AEEVKGRIHQ LLARASYKQA ILLTREATSR 540
FQESEPFSHT EPEEKDFLNL LGVIFKGPEA STHESPRHTD PGLTGSKDSP SVPEPEGSQR 600
DDELLKQEML VQYLQDAYSF SQKITEAIGV ISKMMYENTT TVVQEVIEFF VMVFQFGVPQ 660
ALFGVRRMLP LIWSKELGVR EAVLNAYRQL YLSPKGDSAR ATAQALIQNL SLLLVDASVG 720
TIQCLEEILC EFVQKDEIKP AVIQLLWERA TEKVPCSPLE RCSSVMLLGM MARGKPEIVG 780
SNLDTLVKVG LDEKFPQDYR LAQQVCLAIA NISDRRKPSL GERHPPFRLP QEHKLFERLQ 840
EMVTKGFAHP DPFWIPFKEV AVTLTYQLAE GPDVICSQML QGCAKQALEK LEKNTTEGDS 900
KETAPKLPTF LLMNLLSLAG DVALQQLVHL EQAVSGELGR RRVLREEQEH RTKVPKEKTT 960
SSETTMEEEL GLVGATADDT EAELVRSICE KELLDGTQVL AAFVPLLLKV CNNPGAYSNP 1020
ELSAAASLAL GKFCMISAPF CDSQLRLLFT MLEKSSLPTV RSNLMVATGD LAIRFPNLVD 1080
PWTPHLYARL RDPAQQVRRT AGLVMTHLIL KDMVKVKGQV SEMAVLLIDP VPQIAALAKN 1140
FFNELSHKGN AIYNLLPDII SRLSDPEGGV GEEPFHTIMK QLLSYITKDK QTESLVEKLC 1200
QRFRTARTER QYRDLAYCVS QLPLTERGLH KMLDNFDCFG DKLIDESVFS AFLSIVGKLR 1260
RGAKPEGKAV IDEFEQKLRA CHTRGMDGIE ELETGQGGSQ RALSAKKPSA VSRQQPLTSV 1320
DSDNDFVTPK PRRTKPRRPQ TQQRKSQRKA KVVFSSDESS EDELSAEMTE EETPKKTTPI 1380
RRASAQRHRS 1390 
Gene Ontology
 GO:0000796; C:condensin complex; IEA:Compara.
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0000228; C:nuclear chromosome; IEA:Compara.
 GO:0045120; C:pronucleus; IEA:Compara.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007076; P:mitotic chromosome condensation; IEA:InterPro. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR026971; CND1/NCAPD3.
 IPR007673; Condensin_cplx_su1.
 IPR024324; Condensin_cplx_su1_N. 
Pfam
 PF12922; Cnd1_N 
SMART
  
PROSITE
  
PRINTS