CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031594
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Eukaryotic translation initiation factor 2 beta 
Protein Synonyms/Alias
  
Gene Name
 EIF2S2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
99DEAEEGVKDLKIESGubiquitination[1]
205EKRKFVMKPPQVVRVubiquitination[1]
227VNFTDICKLLHRQPKubiquitination[1]
265IKGRFQQKQIENVLRubiquitination[1]
293SPDTILQKDTRLYFLubiquitination[1]
315RCSVASIKTGFQAVTubiquitination[1]
324GFQAVTGKRAQLRAKubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 
Functional Description
  
Sequence Annotation
  
Keyword
 Initiation factor; Protein biosynthesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 333 AA 
Protein Sequence
MSGDEMIFDP TMSKKKKKKK KPFMLDEEGD TQTEETQPSE TKEVEPEPTE DKDLEADEED 60
TRKKDASDDL DDLNFFNQKK KKKKTKKIFD IDEAEEGVKD LKIESGVQEP TEPEDDLDIM 120
LGNKKKKKKN VKFPDEDEIL EKDEALEDED NKKDDGISFS NQTGPAWAGS ERDYTYEELL 180
NRVFNIMREK NPDMVAGEKR KFVMKPPQVV RVGTKKTSFV NFTDICKLLH RQPKHLLAFL 240
LAELGTSGSI DGNNQLVIKG RFQQKQIENV LRRYIKEYVT CHTCRSPDTI LQKDTRLYFL 300
QCETCHSRCS VASIKTGFQA VTGKRAQLRA KAN 333 
Gene Ontology
 GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. 
Interpro
 IPR002735; Transl_init_fac_IF2/IF5.
 IPR016189; Transl_init_fac_IF2/IF5_N.
 IPR016190; Transl_init_fac_IF2/IF5_Zn-bd. 
Pfam
 PF01873; eIF-5_eIF-2B 
SMART
 SM00653; eIF2B_5 
PROSITE
  
PRINTS