UniProt Accession

 TOM7_HUMAN; Q9P0U1; O95939 

Genbank Protein ID

 AJ011007; AF150733; BC001732 

Genbank Nucleotide ID

 CAB38060.1; AAF67473.1; AAH01732.1 

Protein Name

 Mitochondrial import receptor subunit TOM7 homolog 

Protein Synonyms/Alias

 Translocase of outer membrane 7 kDa subunit homolog 

Gene Name

 TOMM7 

Gene Synonyms/Alias

 TOM7; TOMM07; AD-014 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
17	QRLQQLFKGSQFAIR	ubiquitination	[1, 2, 3, 4]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels.
 Lee KA, Hammerle LP, Andrews PS, Stokes MP, Mustelin T, Silva JC, Black RA, Doedens JR.
 J Biol Chem. 2011 Dec 2;286(48):41530-8. [PMID: 21987572]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 Required for assembly and stability of the TOM complex. 

Sequence Annotation

  

Keyword

 Complete proteome; Membrane; Mitochondrion; Mitochondrion outer membrane; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 55 AA 

Protein Sequence

Gene Ontology

 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005742; C:mitochondrial outer membrane translocase complex; IDA:BHF-UCL.
 GO:0008320; F:protein transmembrane transporter activity; TAS:BHF-UCL.
 GO:0044267; P:cellular protein metabolic process; TAS:Reactome.
 GO:0030150; P:protein import into mitochondrial matrix; IEA:InterPro.
 GO:0006626; P:protein targeting to mitochondrion; TAS:BHF-UCL. 

Interpro

 IPR012621; Tom7. 

Pfam

 PF08038; Tom7 

SMART

  

PROSITE

  

PRINTS