UniProt Accession

 A4D0V4_HUMAN; A4D0V4 

Genbank Protein ID

 AK314808; CH236947; CH471070 

Genbank Nucleotide ID

 BAG37333.1; EAL24358.1; EAW83513.1 

Protein Name

 Capping protein (Actin filament) muscle Z-line, alpha 2 

Protein Synonyms/Alias

 Capping protein (Actin filament) muscle Z-line, alpha 2, isoform CRA_b; cDNA, FLJ95684, Homo sapiens capping protein (actin filament) muscle Z-line, alpha2 (CAPZA2), mRNA 

Gene Name

 CAPZA2 

Gene Synonyms/Alias

 hCG_37884; tcag7.31 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
19	EKVRIAAKFIIHAPP	ubiquitination	[1]
133	TALRAYVKEHYPNGV	ubiquitination	[1]
226	SNEVQTAKEFIKIVE	ubiquitination	[1]
273	RTKIDWNKILSYKIG	ubiquitination	[2]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Actin-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 286 AA 

Protein Sequence

Gene Ontology

 GO:0030863; C:cortical cytoskeleton; IEA:Compara.
 GO:0005737; C:cytoplasm; IDA:HPA.
 GO:0008290; C:F-actin capping protein complex; IEA:InterPro.
 GO:0016020; C:membrane; IEA:Compara.
 GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. 

Interpro

 IPR017865; F-actin_cap_asu_CS.
 IPR002189; WASH_F-actin_cap_alpha. 

Pfam

 PF01267; F-actin_cap_A 

SMART

  

PROSITE

 PS00748; F_ACTIN_CAPPING_A_1
 PS00749; F_ACTIN_CAPPING_A_2 

PRINTS

 PR00191; FACTINCAPA.