CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040317
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 GTPase-activating protein and VPS9 domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 Gapvd1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
133NKFIGYLKQNTYCFPacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 835 AA 
Protein Sequence
XNCIMQEDES YLLQVLRYLI EFELKESDNP RRLLRRGTCA FSILFKLFSE GLFSAKLFLT 60
ATLHEPIMQL LVEDEDHLET DPNKLIERFS PAQQEKLFGE KGSDRFRQKV QEMVDSNEAK 120
LVALVNKFIG YLKQNTYCFP HSLRWIVSQM YKTLSCVDRL EVGEVRAMCT DLLLACFICP 180
AVVNPEQYGI ISDAPINEVA RFNLMQVGRL LQQLAMTGTE EGDPRTKNSL GKFDKGCVAA 240
FLDVVIGGRA VETPPMSSVN LLEGLSRTVV YISYSQLITL VNFMKSVMSG DQLKEDRMAL 300
DNLLANLPQA KPGKSSSLDM TPYSTPQMSP ATTPANKKNR LPIATRSRSR SNMLMDLHMD 360
HEGSSQETIQ EVQPEEVLVI SLGTGPQLTP GMMSENEVLN MQLSDGGQGD VPVDENKLHG 420
KPDKTLRFSL CSDNLEGISE GPSNRSNSVS SLDLEGESVS ELGAGPSGSN GVEALQLLEH 480
EQATTQDNLD DKLRKFEIRD MMGLTDDRDI SETVSETWST DVLGSDFDPN VDEDRLQEIA 540
GAAAENVLGS LLCLPGSGSV LLDPCTGSTI SETTSEAWSV EVLPSDSEAP DLKQEERLQE 600
LESCSGLGST SDDTDVREVS SRPSTPGLSV VSGISATSED IPNKIEDLRS ECSSDFGGKD 660
SVTSPDMDDI AHGASAVVRP KVHYARPSHP PPDPPILEGA VGGNEARLPN FGSHVLTAAE 720
MEAFKQRHSY PERLVRSRSS DIVSSVRRPM SDPSWNRRPG NEELPPAAAT GATSLVAAPH 780
SSSSSPSKDS SRGETEERKD SDDERSDRSR PWWRKRFVSA MPKAPIPFRK KEKQE 835 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0005096; F:GTPase activator activity; IEA:InterPro.
 GO:0043547; P:positive regulation of GTPase activity; IEA:GOC.
 GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR001936; RasGAP.
 IPR008936; Rho_GTPase_activation_prot. 
Pfam
 PF00616; RasGAP 
SMART
  
PROSITE
 PS50018; RAS_GTPASE_ACTIV_2 
PRINTS