UniProt Accession

 H10_RAT; P43278 

Genbank Protein ID

 X72624; BC061842; X70685 

Genbank Nucleotide ID

 CAA51199.1; AAH61842.1; CAA50020.1 

Protein Name

 Histone H1.0 

Protein Synonyms/Alias

 Histone H1'; Histone H1(0); Histone H1.0, N-terminally processed 

Gene Name

 H1f0 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
12	STSTPAAKPKRAKAA	acetylation	[1]
52	SSRQSIQKYIKSHYK	acetylation	[1]
59	KYIKSHYKVGENADS	acetylation	[1]
82	LVTTGVLKQTKGVGA	acetylation	[1]
97	SGSFRLAKGDEPKRS	acetylation	[1]
108	PKRSVAFKKTKKEVK	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. The H1F0 histones are found in cells that are in terminal stages of differentiation or that have low rates of cell division. 

Sequence Annotation

 DOMAIN 24 97 H15.
 MOD_RES 1 1 N-acetylmethionine (By similarity).
 MOD_RES 2 2 N-acetylthreonine; in Histone H1.0, N-  

Keyword

 Acetylation; Chromosome; Complete proteome; DNA-binding; Nucleus; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 194 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0000790; C:nuclear chromatin; IEA:Compara.
 GO:0000786; C:nucleosome; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 

Interpro

 IPR005818; Histone_H1/H5.
 IPR005819; Histone_H5.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00538; Linker_histone 

SMART

 SM00526; H15 

PROSITE

 PS51504; H15 

PRINTS

 PR00624; HISTONEH5.