UniProt Accession

 F8VZA4_HUMAN; F8VZA4 

Genbank Protein ID

 AC024909 

Genbank Nucleotide ID

  

Protein Name

 Dual-specificity protein phosphatase 6 

Protein Synonyms/Alias

  

Gene Name

 DUSP6 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
68	IMLRRLQKGNLPVRA	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 117 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:Compara.
 GO:0030154; P:cell differentiation; IEA:Compara.
 GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IEA:Compara.
 GO:0001933; P:negative regulation of protein phosphorylation; IEA:Compara.
 GO:0006470; P:protein dephosphorylation; IEA:Compara.
 GO:0060420; P:regulation of heart growth; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0070848; P:response to growth factor stimulus; IEA:Compara.
 GO:0014070; P:response to organic cyclic compound; IEA:Compara. 

Interpro

 IPR024950; DUSP.
 IPR001763; Rhodanese-like_dom. 

Pfam

 PF00581; Rhodanese 

SMART

 SM00450; RHOD 

PROSITE

  

PRINTS