| Tag | Content |
|---|
| CPLM ID | CPLM-024101 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Y+L amino acid transporter 1 |
Protein Synonyms/Alias | Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1; Y+LAT1; y+LAT-1 |
Gene Name | Slc7a7 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 6 | **MVNSTKYEVAAQH | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis via transport of L-arginine, and is involved in the transport of L-arginine in monocytes. |
Sequence Annotation | CARBOHYD 3 3 N-linked (GlcNAc...) (Potential).
CARBOHYD 326 326 N-linked (GlcNAc...) (Potential). |
Keyword | Amino-acid transport; Cell membrane; Complete proteome; Disulfide bond; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 510 AA |
Protein Sequence | MVNSTKYEVA AQHEADDGSA LGDGASPVAE QVKLKKEISL LNGVCLIVGN MIGSGIFVSP 60
KGVLMYSASF GLSLVIWAVG GIFSVFGALC YAELGTTIKK SGASYAYILE AFGGFLAFIR 120
LWTSLLIIEP TSQAVIAITF ANYMVQPLFP SCGAPYAAGR LLAAACICLL TFINCAYVKW 180
GTLVQDIFTY AKVLALIAVI IAGIVRLGQG ATANFENSFE GSSFAMGDIA LALYSALFSY 240
SGWDTLNYVT EEIRNPERNL PLSIGISMPI VTIIYLLTNV AYYSVLDIKE ILASDAVAVT 300
FADQIFGVFN WIIPVAVAFS CFGGLNASIV AASRLLFVGS REGHLPDAIC MVHVERFTPV 360
PSLLFNGVLS LVYLCVEDIF QLINYYSFSY WFFVGLSIVG QLYLRWKDPD RPRPLKLSLF 420
FPIIFCLCTI FLVAVPLYSD TINSLIGIGI ALSGLPFYFF IIRVPEHKRP LFLRRIVASI 480
TRYLQILCMS VAAEMDLEDG ELSKQDPKSK 510 |
Gene Ontology | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0015171; F:amino acid transmembrane transporter activity; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |