CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034690
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Frem1 
Protein Synonyms/Alias
  
Gene Name
 Frem1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
2139LWAISGRKPFWIGLKacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2209 AA 
Protein Sequence
MHSPGCTGPK ALLFLLLQLL MLHLDPANAT FISINRGLRV MKGSSAFLSG DHLRFAIPKE 60
KDACRVEVVM NEPITQRVGK LIPQVFDCHF LPNEVQYVHN GCPILDEDSV KLRLYRFTET 120
ETFMETFLLR VSLVEPDCNI IRLSSNVLEV TEFYGLSQAI DKNLLQFDYD RTASLDCTIR 180
VDPVKTQLPA HGKLVVVNRK SEGPRGDQPH SFFSESQLGA ERKCPDGSCT LEPKQVTSLK 240
VSCEDFLLTG FHYQHMQPPS PNIDYIPIQL DLTDRRSKTI YKSESAWLPV FIRVGIPNQA 300
PRAAFMAMFV LEVDQFILTP LTTSVLDCEE DETPKPLLVF NITEAPLQGY VTHLLDHTRP 360
ISSFTWKDLS DMQVAYQPPN NSHPERRHYK MELEVYDLFF ERSAPITVHI SIRTADTNAP 420
RVSWNTGLNL LEGQSRAITW EQFQIVDNDD IGAVQLVTIG GLQHGRLTVR EGKGFLFTVA 480
DLQAGVVRYH HDDSDTTKDF VAFRIFDGQH SSHHKFPINI LPKDDSPPFL ITNVVIELEE 540
GKTILIQGSM LRASDMDSSD DYIFFNITKF PQAGEIMKKP GPRLIGYPVS GFLQRDLFSG 600
IIYYRHFGGE IFEDSFEFVL WDSHEPPNLS VPQVVMVHIT PVDDQLPKEA PGISRHLIVK 660
ETEVAYITKK HLHFLDTESH GGELVYTITR PPCFSSSHRH LDAGKLFMVD SIPKPTKNPT 720
APGLNSFTQV KRFGKTLANT VSTLLGGLGL GCSNIVISVN QCICASQFAS QHAVNHMKVA 780
YMPPMQDIGP TPRHVQFTVS VSNQHGGTLH GICFNITVLP VDNQVPEVFT NTLRVAEGGQ 840
CTISTEHILV SDVDTPLDSI CLSLQEMPLH GGVELDGFPL NPRGTFSWRD LHTLKVRYQH 900
DGSEVLQDEI FLEVTDGTNS AGFVLYIEVF PVNDEPPVLK ADLIPMMHCS EGGEVTITPE 960
YIFATDADSN DSELLFLITR EPRHGVVRKA GLRVDRFSQG DVISGAVAYK HTGGEIGLES 1020
CFDTVVLVVS DGEADPLVNG CCYNGPDSSV PLHKSFPTYQ LNITVHPVDN QPPSIIIGRT 1080
LTVDEGFSAA LTTHHLTATD WDTAPDDLEF ILVSHPQFGY LENTLPSAGF EKRNTGISIA 1140
SFQWRDMKAS HINYVQSRHL REEPTADEFL VYATDGKQRS LETTFHVIIN PTNDEAPDFV 1200
VQNITVYEGH MVELDSAIIS ATDRDVPKDP LLFNITHKPK HGLLLISATS KDAHNEIHNF 1260
SMELLQNGMK LAYAHDDSES SADNFVIQLS DGKHKILKTV SVSITPVNDE TPTLSKKAEV 1320
SVTVGDTRVL SSAVLSAIDK DSPREKIHYL FERLPQNGQL QLKIGRDWVP LSAGMQCTQE 1380
DVDLNLLRYA HAGKMHSQDG DRFTFYLWDG DNRSPAFDCH IIIEDTGRGD IVIHAKPLVV 1440
ANGDRGLLTP ATLLAEDGAD KAEELLYLIT SPPQYGQVEY VYSPGVPITS FSQMDIAGQA 1500
VCYIHKSRTA VLSDSFRFTI SNGLQTQQGV FEITLQGVDS ALPVLTRNRR LRLVEGAMGL 1560
LSTDHLQLTD PDTPPENLTF FLVQLPRHGY LYLRGKVLQH NFTQQDVDSR VVAYQHAGGG 1620
AQEDCFTFLA TDRKNQGFVV DGKVQKEPVL FIIQVDQLDK KAPRITRLHS PSQVGLLKNG 1680
CYGIYITSHV LKASDPDTED DQIIFKILRG PLHGRLENTT TGEFIHEQFS QKDLSRKTIL 1740
YIINPSLQVN SDILEFQAMD PTGNTAPPQR LELKWSYIEW SQTEYEVCEN VGLLTLEVTR 1800
RGYSMDSAYV DIEVNQVSAV VGKDFTVTPS KLLQFDPGMS TKMWNIAITY DGLEEDDEVF 1860
EVILNSPVNA VLGTQTKAAV KILDSKGGRC HPSNSFNQSK HSTWGKGRWH PLPSGSSSLT 1920
TSGSPHLERR PPPSITKGDA LRGFDLTDLS QRKMTTQGNG KSVLPSSVCR NGTDTIYNYH 1980
GIVSLKLEGD RFSAHKRKAK ISVIRQPQRT VKVAELPLAD KVEPTTDSNF LSQGLRPLFP 2040
KNCSVELKGL FHLEEHTHRL YQCDGIAWNV WSSQTKGLED RSCPVGWLLH SDYCHVLVTR 2100
QKGTWATATR ACREQHQGTL VTVFSRRHMQ WLWAISGRKP FWIGLKNQVR TGHWEWIGGE 2160
PVAFTNWRRG PPLHPKPGKN CVLVQRRGQW QTKNCSKGKA HNFVCSRKL 2209 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0030246; F:carbohydrate binding; IEA:InterPro.
 GO:0007154; P:cell communication; IEA:InterPro.
 GO:0007156; P:homophilic cell adhesion; IEA:InterPro. 
Interpro
 IPR001304; C-type_lectin.
 IPR016186; C-type_lectin-like.
 IPR016187; C-type_lectin_fold.
 IPR002126; Cadherin.
 IPR003644; Calx_beta. 
Pfam
 PF03160; Calx-beta
 PF00059; Lectin_C 
SMART
 SM00112; CA
 SM00034; CLECT 
PROSITE
 PS50041; C_TYPE_LECTIN_2 
PRINTS