CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036896
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Abl interactor 2 
Protein Synonyms/Alias
  
Gene Name
 ABI2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
43NYIQSADKQRALEETubiquitination[1]
139RPVRYIRKPIDYTILubiquitination[1]
167KVSTQNMKMGGLPRTubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 486 AA 
Protein Sequence
MAELQMLLEE EIPGGRRALF DSYTNLERVA DYCENNYIQS ADKQRALEET KAYTTQSLAS 60
VAYLINTLAN NVLQMLDIQA SQLRRMESSI NHISQTVDIH KEKVARREIG ILTTNKNTSR 120
THKIIAPANL ERPVRYIRKP IDYTILDDIG HGVKWLLRFK VSTQNMKMGG LPRTTPPTQK 180
PPSPPMSGKG TLGRHSPYRT LEPVRPPVVP NDYVPSPTRN MAPSQQSPVR TASVNQRNRT 240
YSSSGSSGGS HPSSRSSSRE NSGSGSVGVP IAVPTPSPPS VFPAPAGSAG TPPLPATSAS 300
APAPLVPATV PSSTAPDAAA GGAQTLADGF TSPTPPVVSS TPPTGHPVQF YSMNRPASRH 360
TPPTIGGSLP YRRPPSITSQ TSLQNQMNGG PFYSQNPVSD TPPPPPPVEE PVFDESPPPP 420
PPPEDYEEEE AAVVEYSDPY AEEDPPWAPR SYLEKVVAIY DYTKDKEDEL SFQEGAIIYV 480
IKKNDD 486 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro. 
Interpro
 IPR012849; Abl-interactor_HHR_dom.
 IPR001452; SH3_domain.
 IPR000727; T_SNARE_dom. 
Pfam
 PF07815; Abi_HHR
 PF00018; SH3_1 
SMART
 SM00326; SH3 
PROSITE
 PS50002; SH3
 PS50192; T_SNARE 
PRINTS