CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024826
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 D6.1A protein 
Protein Synonyms/Alias
 Protein Tspan8; Tetraspanin 8; Tetraspanin 8, isoform CRA_a 
Gene Name
 Tspan8 
Gene Synonyms/Alias
 Tm4sf3; rCG_48677 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
136SETSNEAKEVQKAMIacetylation[1]
163FGAADWGKNFPDAKEacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 235 AA 
Protein Sequence
MAGVSGCLKY SMFFFNFLFW VCGTLILGLA IWLRVSKDGK EIITSGDNGT NPFIAVNILI 60
AVGSIIMVLG FLGCCGAVKE SRCMLLLFFI GLLLILLLQV AAGILGATFK SESSRILNET 120
LYENAKLLSE TSNEAKEVQK AMIAFQSEFK CCGLRFGAAD WGKNFPDAKE SCQCTGSDCE 180
SYNGENVYRT TCLSLIKELV EKNIIIVIGI AFGLAVIEIL GLVFSMVLYC QIGSK 235 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0030195; P:negative regulation of blood coagulation; IDA:RGD. 
Interpro
 IPR000301; Tetraspanin.
 IPR018499; Tetraspanin/Peripherin.
 IPR018503; Tetraspanin_CS.
 IPR008952; Tetraspanin_EC2. 
Pfam
 PF00335; Tetraspannin 
SMART
  
PROSITE
 PS00421; TM4_1 
PRINTS
 PR00259; TMFOUR.