CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015143
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative deoxyribonuclease TATDN1 
Protein Synonyms/Alias
 Hepatocarcinoma high expression protein 
Gene Name
 TATDN1 
Gene Synonyms/Alias
 CDA11 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
27GIYRGVQKHQDDLQDubiquitination[1]
45RAVEIGVKKFMITGGubiquitination[1]
46AVEIGVKKFMITGGNubiquitination[1]
94NNPDLYLKELLNLAEubiquitination[1]
104LNLAENNKGKVVAIGubiquitination[1]
130CPKDTQLKYFEKQFEubiquitination[1]
134TQLKYFEKQFELSEQubiquitination[1]
162AEFLDIMKRNRDRCVubiquitination[1]
210EANLEVLKSIPSEKLubiquitination[1]
236KSTHAGSKYIRTAFPubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 Putative deoxyribonuclease (By similarity). 
Sequence Annotation
 METAL 112 112 Divalent metal cation 1 (By similarity).
 METAL 112 112 Divalent metal cation 2 (By similarity).
 METAL 149 149 Divalent metal cation 2 (By similarity).
 METAL 174 174 Divalent metal cation 2 (By similarity).
 METAL 222 222 Divalent metal cation 1 (By similarity).  
Keyword
 3D-structure; Alternative splicing; Complete proteome; Hydrolase; Metal-binding; Nuclease; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 297 AA 
Protein Sequence
MSRFKFIDIG INLTDPMFRG IYRGVQKHQD DLQDVIGRAV EIGVKKFMIT GGNLQDSKDA 60
LHLAQTNGMF FSTVGCHPTR CGEFEKNNPD LYLKELLNLA ENNKGKVVAI GECGLDFDRL 120
QFCPKDTQLK YFEKQFELSE QTKLPMFLHC RNSHAEFLDI MKRNRDRCVG GVVHSFDGTK 180
EAAAALIDLD LYIGFNGCSL KTEANLEVLK SIPSEKLMIE TDAPWCGVKS THAGSKYIRT 240
AFPTKKKWES GHCLKDRNEP CHIIQILEIM SAVRDEDPLE LANTLYNNTI KVFFPGI 297 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0090305; P:nucleic acid phosphodiester bond hydrolysis; IEA:GOC. 
Interpro
 IPR018228; DNase_TatD-rel_CS.
 IPR001130; TatD_family. 
Pfam
 PF01026; TatD_DNase 
SMART
  
PROSITE
 PS01090; TATD_2
 PS01091; TATD_3 
PRINTS