| Tag | Content |
|---|
| CPLM ID | CPLM-007505 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Maintenance of mitochondrial morphology protein 1 |
Protein Synonyms/Alias | Mitochondrial outer membrane protein MMM1; Yeast mitochondrial escape protein 6 |
Gene Name | MMM1 |
Gene Synonyms/Alias | YME6; YLL006W; L1357 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 233 | LNDFIGRKSPDLPEY | ubiquitination | [1] | | 422 | SKNTREEKPTEL*** | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta-barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 subcomplex further acts in the TOM40-specific pathway after the action of the MDM12-MMM1 complex. Essential for establishing and maintaining the structure of mitochondria and maintenance of mtDNA nucleoids. |
Sequence Annotation | CARBOHYD 6 6 N-linked (GlcNAc...) (Potential).
CARBOHYD 50 50 N-linked (GlcNAc...) (Potential).
CARBOHYD 55 55 N-linked (GlcNAc...) (Potential).
CARBOHYD 59 59 N-linked (GlcNAc...) (Potential). |
Keyword | Complete proteome; Endoplasmic reticulum; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 426 AA |
Protein Sequence | MTDSENESTE TDSLMTFDDY ISKELPEHLQ RLIMENLKGS TTNDLKQTSN NSEFNVSKNG 60
SFKGLDDAIQ ALQMQSVLHP SSLGSLATSS KFSGWSFAQG FFVGQLSIVL LFIFFLKFFI 120
FSDEPSKSKN PKPAASRHRS KFKEYPFISR EFLTSLVRKG AKQHYELNEE AENEHLQELA 180
LILEKTYYNV DVHPAESLDW FNVLVAQIIQ QFRSEAWHRD NILHSLNDFI GRKSPDLPEY 240
LDTIKITELD TGDDFPIFSN CRIQYSPNSG NKKLEAKIDI DLNDHLTLGV ETKLLLNYPK 300
PGIAALPINL VVSIVRFQAC LTVSLTNAEE FASTSNGSSS ENGMEGNSGY FLMFSFSPEY 360
RMEFEIKSLI GSRSKLENIP KIGSVIEYQI KKWFVERCVE PRFQFVRLPS MWPRSKNTRE 420
EKPTEL 426 |
Gene Ontology | GO:0032865; C:ERMES complex; IDA:SGD. GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD. GO:0000002; P:mitochondrial genome maintenance; IMP:SGD. GO:0015914; P:phospholipid transport; IMP:SGD. GO:0045040; P:protein import into mitochondrial outer membrane; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |