CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034831
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Rfc1 
Protein Synonyms/Alias
  
Gene Name
 Rfc1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
314SSLKASSKLALMKAQacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1131 AA 
Protein Sequence
MDIRKFFGVI SSGKKPVNET VKKNEKTKPS EGTVKGKKGV KEAKVNNPCK EDASRPKQHN 60
KKKRIIYDSD SESEETVQVK NAKKKSEKLP VSCKPGKISR KDPVTYISET DEDDDFLCKK 120
AASKSKENGV STNSYLGASN VKKNEENTKT KSKPLSPIKL TPTSVLDYFG TESVQRSGKK 180
MVASKKKESS QTPDDSRLND EAIAKQLQLD EDAELERQLH EDEEFARTLA LLDEEPKTKK 240
ARKDSEEGES FSPAKAELSK AAKQKSPANE HFSIGRKTYS PAKYGKGRGS EGTKQPCRSA 300
HQKEACSSLK ASSKLALMKA QEENSYKETE LLAAKRESAI EPKGEKTTPR KTKGSPTKRE 360
SVSPEDSEKK RTNYQAYRSY LNREGPKALG SKEIPKGAEN CLEGLTFVIT GVLESIEREE 420
AKSLIERYGG KVTGNVSKKT SYLVMGRDSG QSKSDKAAAL GTKILDEDGL LDLIRTMPGK 480
KSKYEIAAEA EMKKEKSKLE RTPQKNDQGK RKLSPTKREL EPKKSKLTPL KHSPRKAVKE 540
EERVCPRGLD AKEPHGSHSA SREECLLWVD KYKPTSLKNI IGQQGDQSCA NKLLRWLRNW 600
HKSSPEEKKH AAKFGKVASK DDGSSFKAAL LSGPPGVGKT TTASLVCQEL GYSYVELNAS 660
DTRSKNSLKA IVAESLNNTS IKGFYTSGAS PSVSARHALI MDEVDGMAGN EDRGGIQELI 720
GLIKHTKIPI ICMCNDRNHP KIRSLVHYCF DLRFQRPRVE QIKSAMLSIA FKEGLKIPPP 780
AMNEIILGAN QDVRQVLHNL SMWCAQSKVL TYDQAKADSQ RAKKDIRLGP FDVTRKVFAA 840
GEETAHMSLM DKSDLFFHDY SIAPLFVQEN YLHVKPVAAG GDMKKHLMLL SRAADSICDG 900
DLVDNQIRSK QNWSLLPTQA IYASVVPGEL MRGYMSQFPS FPSWLGKHSS TGKHDRTVQD 960
LSLHMSLRTY SSKRTVNMDY LSHIRDALVR PLTSQGVEGV QRVVTLMDTY YLVKEDFDNI 1020
MEVSSWGGKP STFSKLDPKV KAAFTRAYNK EAHLTPYSLQ VVKASRPSIG PALDSEYNEE 1080
SQEDATQSDE KEQDALETDA MIKQKKTRSS KPSKSEKEKE SKKGKGKNSK K 1131 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:RGD.
 GO:0005663; C:DNA replication factor C complex; IEA:Compara.
 GO:0005730; C:nucleolus; IDA:RGD.
 GO:0043234; C:protein complex; IDA:RGD.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0003689; F:DNA clamp loader activity; IEA:InterPro.
 GO:0003690; F:double-stranded DNA binding; IDA:RGD.
 GO:0043565; F:sequence-specific DNA binding; IDA:RGD.
 GO:0006260; P:DNA replication; IEA:InterPro.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:RGD.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:RGD. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003959; ATPase_AAA_core.
 IPR001357; BRCT_dom.
 IPR008921; DNA_pol3_clamp-load_cplx_C.
 IPR012178; DNA_replication_fac_C_lsu.
 IPR013725; DNA_replication_fac_RFC1_C.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00004; AAA
 PF00533; BRCT
 PF08519; RFC1 
SMART
 SM00382; AAA
 SM00292; BRCT 
PROSITE
 PS50172; BRCT 
PRINTS