60 kDa chaperonin; Chaperonin 60; CPN60; HSP-65; Heat shock protein 60; HSP-60; Hsp60; Mitochondrial matrix protein P1
Gene Name
Hspd1
Gene Synonyms/Alias
Hsp60
Created Date
July 27, 2013
Organism
Rattus norvegicus (Rat)
NCBI Taxa ID
10116
Lysine Modification
Position
Peptide
Type
References
31
RAYAKDVKFGADARA
acetylation
[1]
91
IDLKDKYKNIGAKLV
acetylation
[1]
96
KYKNIGAKLVQDVAN
acetylation
[1]
130
IAKEGFEKISKGANP
acetylation
[1]
133
EGFEKISKGANPVEI
acetylation
[1]
156
DAVIAELKKQSKPVT
acetylation
[1]
160
AELKKQSKPVTTPEE
acetylation
[1]
180
TISANGDKDIGNIIS
acetylation
[1]
202
RKGVITVKDGKTLND
acetylation
[1]
205
VITVKDGKTLNDELE
acetylation
[1]
218
LEIIEGMKFDRGYIS
acetylation
[1]
269
EIANAHRKPLVIIAE
acetylation
[1]
314
DNRKNQLKDMAIATG
acetylation
[1]
369
GDKAHIEKRIQEITE
acetylation
[1]
387
ITTSEYEKEKLNERL
acetylation
[1]
396
KLNERLAKLSDGVAV
acetylation
[1]
455
IPALDSLKPANEDQK
acetylation
[1]
516
DFVNMVEKGIIDPTK
acetylation
[1]
Reference
[1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
Functional Description
Implicated in mitochondrial protein import and macromolecular assembly. May facilitate the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.