| Tag | Content |
|---|
| CPLM ID | CPLM-007956 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Transcription initiation factor TFIID subunit 4 |
Protein Synonyms/Alias | 110 kDa TBP-associated factor; Transcription initiation factor TFIID 110 kDa subunit; TAFII-110; p110 |
Gene Name | Taf4 |
Gene Synonyms/Alias | TAF110; CG5444 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 507 | NSVPTANKLTAVKVG | acetylation | [1] | | 630 | RPPPAINKAIGKKKR | acetylation | [1] | | 634 | AINKAIGKKKRDAME | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May function as a coactivator by serving as a site of protein-protein contact between activators like Sp1 (or btd) and TFIID complex. |
Sequence Annotation | DOMAIN 290 386 TAFH. |
Keyword | Alternative splicing; Complete proteome; Direct protein sequencing; Nucleus; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 921 AA |
Protein Sequence | MNTSQTAAGN RITFTSQPLP NGTISIAGNP GAVISTAQLP NTTTIKTIQA GIGGQHQGLQ 60
QVHHVQQQQQ SQQQQQQQQQ TQSAGQPLLN SMLPAGVVVG MRQQAPSQQQ QKNVPTNPLS 120
RVVINSHMAG VRPQSPSITL STLNTGQTPA LLVKTDNGFQ LLRVGTTTGP PTVTQTITNT 180
SNNSNTTSTT NHPTTTQIRL QTVPAAASMT NTTATSNIIV NSVASSGYAN SSQPPHLTQL 240
NAQAPQLPQI TQIQTIPAQQ SQQQQVNNVS SAGGTATAVS STTAATTTQQ GNTKEKCRKF 300
LANLIELSTR EPKPVEKNVR TLIQELVNAN VEPEEFCDRL ERLLNASPQP CLIGFLKKSL 360
PLLRQALYTK ELVIEGIKPP PQHVLGLAGL SQQLPKIQAQ IRPIGPSQTT TIGQTQVRMI 420
TPNALGTPRP TIGHTTISKQ PPNIRLPTAP RLVNTGGIRT QIPSLQVPGQ ANIVQIRGPQ 480
HAQLQRTGSV QIRATTRPPN SVPTANKLTA VKVGQTQIKA ITPSLHPPSL AAISGGPPPT 540
PTLSVLSTLN SASTTTLPIP SLPTVHLPPE ALRAREQMQN SLNHNSNHFD AKLVEIKAPS 600
LHPPHMERIN ASLTPIGAKT MARPPPAINK AIGKKKRDAM EMDAKLNTSS GGAASAANSF 660
FQQSSMSSMY GDDDINDVAA MGGVNLAEES QRILGCTENI GTQIRSCKDE VFLNLPSLQA 720
RIRAITSEAG LDEPSQDVAV LISHACQERL KNIVEKLAVI AEHRIDVIKL DPRYEPAKDV 780
RGQIKFLEEL DKAEQKRHEE LEREMLLRAA KSRSRVEDPE QAKMKARAKE MQRAEMEELR 840
QRDANLTALQ AIGPRKKLKL DGETVSSGAG SSGGGVLSSS GSAPTTLRPR IKRVNLRDML 900
FYMEQEREFC RSSMLFKTYL K 921 |
Gene Ontology | GO:0005669; C:transcription factor TFIID complex; IPI:UniProtKB. GO:0003677; F:DNA binding; IDA:UniProtKB. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0048813; P:dendrite morphogenesis; IMP:FlyBase. GO:0007517; P:muscle organ development; IMP:FlyBase. GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase. GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IDA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |