CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-043942
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Probable cation-transporting ATPase 13A1 
Protein Synonyms/Alias
  
Gene Name
 ATP13A1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
62PSKATFVKVVPTPNNubiquitination[1, 2]
95VLSFEFQKIKYSYDAubiquitination[2, 3, 4, 5]
97SFEFQKIKYSYDALEubiquitination[4]
105YSYDALEKKQFLPVAubiquitination[2]
106SYDALEKKQFLPVAFubiquitination[3, 4, 5, 6]
145EKKFGSNKAEMVVPDubiquitination[4]
158PDFSELFKERATAPFubiquitination[2, 3, 4, 5]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [5] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [6] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 185 AA 
Protein Sequence
XASPWVPAAA FLSVTIATWA THLPGLDSQG HPLHFGAGLI MTPLLTCCAC LEYDPSKATF 60
VKVVPTPNNG STELVALHRN EGEDGLEVLS FEFQKIKYSY DALEKKQFLP VAFPVGNAFS 120
YYQSNRGFQE DSEIRAAEKK FGSNKAEMVV PDFSELFKER ATAPFFVFQV FCVGLWCLDE 180
YWYYS 185 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR006544; ATPase_P-typ_Cation_typ_V.
 IPR001757; Cation_transp_P_typ_ATPase. 
Pfam
  
SMART
  
PROSITE
  
PRINTS