CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017964
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Arrestin domain-containing protein 2 
Protein Synonyms/Alias
  
Gene Name
 ARRDC2 
Gene Synonyms/Alias
 PP2703 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
147VPARRARKVFTVIEPubiquitination[1]
189GLVSLSAKIDRKGYTubiquitination[1, 2]
193LSAKIDRKGYTPGEVubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Alternative splicing; Complete proteome; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 407 AA 
Protein Sequence
MLFDKVKAFS VQLDGATAGV EPVFSGGQAV AGRVLLELSS AARVGALRLR ARGRAHVHWT 60
ESRSAGSSTA YTQSYSERVE VVSHRATLLA PDTGETTTLP PGRHEFLFSF QLPPTLVTSF 120
EGKHGSVRYC IKATLHRPWV PARRARKVFT VIEPVDINTP ALLAPQAGAR EKVARSWYCN 180
RGLVSLSAKI DRKGYTPGEV IPVFAEIDNG STRPVLPRAA VVQTQTFMAR GARKQKRAVV 240
ASLAGEPVGP GQRALWQGRA LRIPPVGPSI LHCRVLHVDY ALKVCVDIPG TSKLLLELPL 300
VIGTIPLHPF GSRSSSVGSH ASFLLDWRLG ALPERPEAPP EYSEVVADTE EAALGQSPFP 360
LPQDPDMSLE GPFFAYIQEF RYRPPPLYSE EDPNPLLGDM RPRCMTC 407 
Gene Ontology
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR011021; Arrestin-like_N.
 IPR014752; Arrestin_C.
 IPR011022; Arrestin_C-like.
 IPR014756; Ig_E-set. 
Pfam
 PF02752; Arrestin_C
 PF00339; Arrestin_N 
SMART
 SM01017; Arrestin_C 
PROSITE
  
PRINTS