UniProt Accession

 H0W1Z7_CAVPO; H0W1Z7 

Genbank Protein ID

 AAKN02051317 

Genbank Nucleotide ID

  

Protein Name

 Uncharacterized protein 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Cavia porcellus (Guinea pig) 

NCBI Taxa ID

 10141 

Lysine Modification

Position	Peptide	Type	References
91	IDLKDKYKNIGAKLV	acetylation	[1]
125	VLARSIAKEGFEKIS	acetylation	[1]
130	IAKEGFEKISKGANP	acetylation	[1]
191	NIISDAMKKVGRKGV	acetylation	[1]
192	IISDAMKKVGRKGVI	acetylation	[1]
202	RKGVITVKDGKTLND	acetylation	[1]
249	AYVLLSEKKISSVQS	acetylation	[1]
250	YVLLSEKKISSVQSI	acetylation	[1]
352	VGEVIVTKDDAMLLK	acetylation	[1]
359	KDDAMLLKGKGDKAQ	acetylation	[1]
364	LLKGKGDKAQIEKRI	acetylation	[1]
387	VTTSEYEKEKLNERL	acetylation	[1]
389	TSEYEKEKLNERLKL	acetylation	[1]
416	SDVEVNEKKDRVTDA	acetylation	[1]
417	DVEVNEKKDRVTDAL	acetylation	[1]
468	KIGIEIIKRTLKIPA	acetylation	[1]
472	EIIKRTLKIPAMTIA	acetylation	[1]

Reference

 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019] 

Functional Description

  

Sequence Annotation

  

Keyword

 ATP-binding; Chaperone; Complete proteome; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 563 AA 

Protein Sequence

Gene Ontology

 GO:0009986; C:cell surface; IEA:Compara.
 GO:0005905; C:coated pit; IEA:Compara.
 GO:0030135; C:coated vesicle; IEA:Compara.
 GO:0019907; C:cyclin-dependent protein kinase activating kinase holoenzyme complex; IEA:Compara.
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0005769; C:early endosome; IEA:Compara.
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0046696; C:lipopolysaccharide receptor complex; IEA:Compara.
 GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
 GO:0030141; C:secretory granule; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0001530; F:lipopolysaccharide binding; IEA:Compara.
 GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IEA:Compara.
 GO:0002368; P:B cell cytokine production; IEA:Compara.
 GO:0042100; P:B cell proliferation; IEA:Compara.
 GO:0048291; P:isotype switching to IgG isotypes; IEA:Compara.
 GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; IEA:Compara.
 GO:0043066; P:negative regulation of apoptotic process; IEA:Compara.
 GO:0043065; P:positive regulation of apoptotic process; IEA:Compara.
 GO:0032727; P:positive regulation of interferon-alpha production; IEA:Compara.
 GO:0032729; P:positive regulation of interferon-gamma production; IEA:Compara.
 GO:0032733; P:positive regulation of interleukin-10 production; IEA:Compara.
 GO:0032735; P:positive regulation of interleukin-12 production; IEA:Compara.
 GO:0032755; P:positive regulation of interleukin-6 production; IEA:Compara.
 GO:0043032; P:positive regulation of macrophage activation; IEA:Compara.
 GO:0050870; P:positive regulation of T cell activation; IEA:Compara.
 GO:0002842; P:positive regulation of T cell mediated immune response to tumor cell; IEA:Compara.
 GO:0042026; P:protein refolding; IEA:Compara.
 GO:0006986; P:response to unfolded protein; IEA:Compara.
 GO:0042110; P:T cell activation; IEA:Compara. 

Interpro

 IPR018370; Chaperonin_Cpn60_CS.
 IPR001844; Chaprnin_Cpn60.
 IPR002423; Cpn60/TCP-1.
 IPR027409; GroEL-like_apical_dom.
 IPR027413; GROEL-like_equatorial. 

Pfam

 PF00118; Cpn60_TCP1 

SMART

  

PROSITE

 PS00296; CHAPERONINS_CPN60 

PRINTS

 PR00298; CHAPERONIN60.