CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003099
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Primosomal protein 1 
Protein Synonyms/Alias
 Primosomal protein I 
Gene Name
 dnaT 
Gene Synonyms/Alias
 b4362; JW4326 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
143HHVQWQQKLARSLQIacetylation[1]
Reference
 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618
Functional Description
 This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'. 
Sequence Annotation
  
Keyword
 Complete proteome; Direct protein sequencing; DNA replication; Primosome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 179 AA 
Protein Sequence
MSSRVLTPDV VGIDALVHDH QTVLAKAEGG VVAVFANNAP AFYAVTPARL AELLALEEKL 60
ARPGSDVALD DQLYQEPQAA PVAVPMGKFA MYPDWQPDAD FIRLAALWGV ALREPVTTEE 120
LASFIAYWQA EGKVFHHVQW QQKLARSLQI GRASNGGLPK RDVNTVSEPD SQIPPGFRG 179 
Gene Ontology
 GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
 GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-KW.
 GO:0006267; P:pre-replicative complex assembly; IPI:EcoCyc. 
Interpro
 IPR020917; Primosomal_protein_1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS