UniProt Accession

 E5KN55_HUMAN; E5KN55 

Genbank Protein ID

 HQ205146; HQ205147; HQ205148; HQ205149; HQ205151; HQ205152; HQ205153; HQ205154; HQ205155; HQ205156; HQ205157; HQ205158; HQ205159; HQ205160; HQ205161; HQ205162; HQ205163; HQ205165; HQ205166; HQ205168; HQ205169; HQ205170; HQ205171; HQ205172; HQ205173; HQ205174; HQ205175; HQ205176; HQ205177; HQ205178; HQ205179; HQ205180; HQ205181; HQ205182; HQ205183; HQ205184; HQ205185 

Genbank Nucleotide ID

 ADP90614.1; ADP90615.1; ADP90616.1; ADP90617.1; ADP90619.1; ADP90620.1; ADP90621.1; ADP90622.1; ADP90623.1; ADP90624.1; ADP90625.1; ADP90626.1; ADP90627.1; ADP90628.1; ADP90629.1; ADP90630.1; ADP90631.1; ADP90633.1; ADP90634.1; ADP90636.1; ADP90637.1; ADP90638.1; ADP90639.1; ADP90640.1; ADP90641.1; ADP90642.1; ADP90643.1; ADP90644.1; ADP90645.1; ADP90646.1; ADP90647.1; ADP90648.1; ADP90649.1; ADP90650.1; ADP90651.1; ADP90652.1; ADP90653.1 

Protein Name

 Peptidyl-prolyl cis-trans isomerase D 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
218	IDLKDVDKILLITED	ubiquitination	[1, 2]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

  

Keyword

 Isomerase; Rotamase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 370 AA 

Protein Sequence

Gene Ontology

 GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.
 GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
 GO:0006457; P:protein folding; IEA:UniProtKB-KW.
 GO:0000413; P:protein peptidyl-prolyl isomerization; IEA:GOC. 

Interpro

 IPR002130; Cyclophilin-like_PPIase_dom.
 IPR020892; Cyclophilin-type_PPIase_CS.
 IPR013026; TPR-contain_dom.
 IPR011990; TPR-like_helical.
 IPR019734; TPR_repeat. 

Pfam

 PF00160; Pro_isomerase
 PF13176; TPR_7 

SMART

 SM00028; TPR 

PROSITE

 PS00170; CSA_PPIASE_1
 PS50072; CSA_PPIASE_2
 PS50005; TPR
 PS50293; TPR_REGION 

PRINTS

 PR00153; CSAPPISMRASE.