CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015719
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable protein phosphatase CG10417 
Protein Synonyms/Alias
  
Gene Name
 CG10417 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
300TELNQSSKNEFTNSSacetylation[1]
310FTNSSTSKEFERNINacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
 METAL 57 57 Manganese 1 (By similarity).
 METAL 57 57 Manganese 2 (By similarity).
 METAL 58 58 Manganese 1; via carbonyl oxygen (By
 METAL 506 506 Manganese 2 (By similarity).
 METAL 555 555 Manganese 2 (By similarity).
 MOD_RES 289 289 Phosphoserine.
 MOD_RES 306 306 Phosphoserine.
 MOD_RES 592 592 Phosphoserine.
 MOD_RES 594 594 Phosphoserine.
 MOD_RES 599 599 Phosphoserine.
 MOD_RES 637 637 Phosphothreonine.
 MOD_RES 639 639 Phosphoserine.
 MOD_RES 641 641 Phosphoserine.  
Keyword
 Complete proteome; Hydrolase; Magnesium; Manganese; Metal-binding; Phosphoprotein; Protein phosphatase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 662 AA 
Protein Sequence
MGAYLSHPKT DKTSTDQFNE LLAVGASSMQ GWRNSQEDAH NSILNFDNNT SFFAVYDGHG 60
GAEVAQYCAD KLPHFLKNLE TYKNGQFEVA LKEAFLGFDK TLLDPSIVSI LKILAGEHNF 120
VDAEADDYEE EDLAELQEES NLPLNEVLEK YKGLPQKKDL DLKSSDHKEN FKMRSPYFRG 180
RRAAALAAEA TNKAVMDPSA KPDGSSTSAA AAAAALSADG VANSRNPSNV VNPMAGADSN 240
TTTSINDLST KNAALKDDSV NDQNEGSNGT DFKHTLVSSS NKKLFATGSN DMTELNQSSK 300
NEFTNSSTSK EFERNINSSQ DDEFTDDDAD YEENDNVKSP DTSSAESSDC TENDDDGDED 360
GNEDSDEEET DEDQMANDNF CANMIEEPGK DSGCTAVVCL LQGRDLYVAN AGDSRCVISR 420
SGQAIEMSID HKPEDDEEAS RIIKAGGRVT LDGRVNGGLN LSRALGDHAY KTNVTLPAEE 480
QMISALPDIK KLIITPEDEF MVLACDGIWN YMSSEEVVEF VRCRLKDNKK LSTICEELFD 540
NCLAPNTMGD GTGCDNMTAV IVQFKKKLQE LQSTIPPNQT EDKLLKTSEN VSHSLNDQSA 600
SKRCASQNAD ADDEILEKNN SKRLKTDLEQ ENIKDRTPSP SNQNEDPTQK AIKEVTIIVS 660
SS 662 
Gene Ontology
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0004722; F:protein serine/threonine phosphatase activity; NAS:FlyBase.
 GO:0006470; P:protein dephosphorylation; NAS:FlyBase. 
Interpro
 IPR001932; PP2C-like.
 IPR000222; PP2C_Mn2_Asp60_BS.
 IPR015655; Protein_Pase_2C. 
Pfam
 PF00481; PP2C 
SMART
 SM00331; PP2C_SIG
 SM00332; PP2Cc 
PROSITE
 PS01032; PP2C 
PRINTS