CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042177
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Phosphorylase 
Protein Synonyms/Alias
  
Gene Name
 LOC100722429 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
794EKVSNLYKNPREWTRacetylation[1]
812RNIATSGKFSSDRTIacetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019
Functional Description
 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity). 
Sequence Annotation
  
Keyword
 Carbohydrate metabolism; Complete proteome; Glycosyltransferase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 843 AA 
Protein Sequence
MSRPLSDQER RKQISVRGLA GVENVTELKK NFNRHLHFTL VKDRNVATPR DYYFALAHTV 60
RDHLVGRWIR TQQHYYEKDP KRIYYLSLEF YMGRTLQNTM VNLALENACD EATYQLGLDM 120
EELEEIEEDA GLGNGGLGRL AAACFLDSMA TLGLAAYGYG IRYEFGIFNQ KKRGGSRMEE 180
ADDWLRYGNP WEKARPEFTL PVHFYGHVEH SSQGAKWVNT QVVLAMPYDT PVPGYRNNVV 240
NTMRLWSAKA PNDFNLKDFN VGGYIQAVLD RNLAENISRV LYPNDNFFEG KELRLKQEYF 300
VVAATLQDII RRFKSSKFGS RDPVRTNFDA FPDKVAIQLN DTHPSLAIPE LMRILVDLER 360
LEWDKAWDIT VKTCAYTNHT VLPEALERWP VHLLETLLPR HLQIIYEINQ RFLNRVAASF 420
PGDVDRLRRM SLVEEGAVKR INMAHLCIAG SHAVNGVARI HSEILKKTIF KDFYELEPHK 480
FQNKTNGITP RRWLVLCNPG LAEVIAERIG EEYISDLDQL RKLLSYVDDE AFIRDVAKVK 540
QENKLKFSAY LEREYKVHIN PNSLFDVQVK RIHEYKRQLL NCLHVITLYN RIKKEPNKFV 600
VPRTVMIGGK AAPGYHMAKM IIRLITAIGD VVNHDPVVGD RLRVIFLENY RVSLAEKVIP 660
AADLSEQIST AGTEASGTGN MKFMLNGALT IGTMDGANVE MAEEAGEENF FIFGMRVEDV 720
DRLDQRGYNA QEYYDRIPEL RQIIEQLSSG FFSPKQPDLF KDIVNMLMHH DRFKVFADYE 780
DYIKCQEKVS NLYKNPREWT RMVIRNIATS GKFSSDRTIA QYAREIWGVE PSRQRLPAPD 840
EKI 843 
Gene Ontology
 GO:0008184; F:glycogen phosphorylase activity; IEA:Compara.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0005980; P:glycogen catabolic process; IEA:Compara. 
Interpro
 IPR011833; Glycg_phsphrylas.
 IPR000811; Glyco_trans_35. 
Pfam
 PF00343; Phosphorylase 
SMART
  
PROSITE
 PS00102; PHOSPHORYLASE 
PRINTS