UniProt Accession

 PMF1_HUMAN; Q6P1K2; A8K0C5; Q5TCJ8; Q5TCJ9; Q5TCK0; Q5TCK1; Q5TCK3; Q69YZ9; Q6PHR4; Q6ZVE6; Q86VJ6; Q8N4T6; Q9UBQ3 

Genbank Protein ID

 AF141309; AF141308; AF141310; AK124646; AK289490; AK290260; AL135927; AL135927; AL135927; AL135927; AL135927; CH471121; CH471121; BC033656; BC050735; BC056417; BC065031; AL080101 

Genbank Nucleotide ID

 AAD50080.1; AAD50080.1; AAD50081.1; BAC85916.1; BAF82179.1; BAF82949.1; CAI15535.1; CAI15536.1; CAI15538.1; CAI15539.1; CAI15540.2; EAW52989.1; EAW52990.1; AAH50735.1; AAH56417.1; AAH65031.1; CAH10730.1 

Protein Name

 Polyamine-modulated factor 1 

Protein Synonyms/Alias

 PMF-1 

Gene Name

 PMF1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
36	GTTISRVKLLDTMVD	ubiquitination	[1]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

 Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis. May act as a cotranscription partner of NFE2L2 involved in regulation of polyamine-induced transcription of SSAT. 

Sequence Annotation

 MOD_RES 2 2 N-acetylalanine.  

Keyword

 Acetylation; Activator; Alternative splicing; Cell cycle; Cell division; Centromere; Chromosome; Chromosome partition; Coiled coil; Complete proteome; Kinetochore; Mitosis; Nucleus; Polymorphism; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 205 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0000444; C:MIS12/MIND type complex; IDA:UniProtKB.
 GO:0005667; C:transcription factor complex; TAS:ProtInc.
 GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.
 GO:0051301; P:cell division; IEA:UniProtKB-KW.
 GO:0007059; P:chromosome segregation; IMP:UniProtKB.
 GO:0007067; P:mitosis; IEA:UniProtKB-KW.
 GO:0000278; P:mitotic cell cycle; TAS:Reactome.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc. 

Interpro

 IPR007128; Nnf1. 

Pfam

 PF03980; Nnf1 

SMART

  

PROSITE

  

PRINTS