CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021402
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable inactive protein kinase-like protein SgK196 
Protein Synonyms/Alias
 Sugen kinase 196 
Gene Name
 SGK196 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
3*****MEKQPQNSRRubiquitination[1]
101RVFLSEWKEHKVALSubiquitination[1]
116QLTSLEMKDDFLHGLubiquitination[1]
311FHLFDIHKACKSQTPubiquitination[1]
314FDIHKACKSQTPSERubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 May be required for the glycosylation of DAG1 alpha- dystroglycan chain. 
Sequence Annotation
 DOMAIN 81 350 Protein kinase.  
Keyword
 ATP-binding; Complete proteome; Congenital muscular dystrophy; Lissencephaly; Membrane; Nucleotide-binding; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 350 AA 
Protein Sequence
MEKQPQNSRR GLAPREVPPA VGLLLIMALM NTLLYLCLDH FFIAPRQSTV DPTHCPYGHF 60
RIGQMKNCSP WLSCEELRTE VRQLKRVGEG AVKRVFLSEW KEHKVALSQL TSLEMKDDFL 120
HGLQMLKSLQ GTHVVTLLGY CEDDNTMLTE YHPLGSLSNL EETLNLSKYQ NVNTWQHRLE 180
LAMDYVSIIN YLHHSPVGTR VMCDSNDLPK TLSQYLLTSN FSILANDLDA LPLVNHSSGM 240
LVKCGHRELH GDFVAPEQLW PYGEDVPFHD DLMPSYDEKI DIWKIPDISS FLLGHIEGSD 300
MVRFHLFDIH KACKSQTPSE RPTAQDVLET YQKVLDTLRD AMMSQAREML 350 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004672; F:protein kinase activity; IEA:InterPro.
 GO:0007420; P:brain development; IEA:Compara.
 GO:0007611; P:learning or memory; IEA:Compara.
 GO:0050905; P:neuromuscular process; IEA:Compara.
 GO:0001764; P:neuron migration; IEA:Compara.
 GO:0019233; P:sensory perception of pain; IEA:Compara. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000719; Prot_kinase_cat_dom.
 IPR001245; Ser-Thr/Tyr_kinase_cat_dom. 
Pfam
 PF07714; Pkinase_Tyr 
SMART
  
PROSITE
 PS50011; PROTEIN_KINASE_DOM 
PRINTS